NCT04998695 (ORUJOSALUD-2) is a NA clinical trial of Olive pomace oil in Healthy, sponsored by Instituto de Ciencia y Tecnología de Alimentos y Nutrición.

Who is sponsoring NCT04998695?

NCT04998695 is sponsored by Instituto de Ciencia y Tecnología de Alimentos y Nutrición.

What drugs are being tested in NCT04998695?

Interventions in NCT04998695: Olive pomace oil, Sunflower oil.

What condition does NCT04998695 study?

NCT04998695 studies Healthy, Hypercholesterolemia.

Is NCT04998695 still recruiting?

NCT04998695 is currently completed. Last updated 16 August 2021.

Last reviewed 2021-08-16 · How we verify

NCT04998695: ORUJOSALUD-2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Health Effects of Consuming Olive Pomace Oil

Completed NA Last updated 16 August 2021

What this trial tests

NA trial testing Olive pomace oil in Healthy in 68 participants. Completed in 20 December 2019.

Timeline

9 September 2019

Primary endpoint
20 December 2019

20 December 2019

Quick facts

Lead sponsor	Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	68
Start date	9 September 2019
Primary completion	20 December 2019
Estimated completion	20 December 2019
Sites	1 location across Spain

Drugs / interventions tested

Olive pomace oil
Sunflower oil — full drug profile →

Conditions studied

Healthy — all drugs for Healthy →
Hypercholesterolemia — all drugs for Hypercholesterolemia →

Sponsor

Instituto de Ciencia y Tecnología de Alimentos y Nutrición

Who can join

Adults 18 to 55, any sex, with Healthy or Hypercholesterolemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Healthy and at risk (hypercholesterolemic) subjects consumed during 4 weeks 45 g/d of either olive pomace oil (OPO) or sunflower oil (SO) as the only dietary fat in a randomized, crossover trial. The effects on blood lipids, glucose homeostasis, endothelial function, inflammatory cytokines, oxidative stress biomarkers and anthropometry were measured.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Olive Pomace Oil versus High Oleic Sunflower Oil and Sunflower Oil: A Comparative Study in Healthy and Cardiovascular Risk Humans.
González-Rámila S, Mateos R, García-Cordero J, Seguido MA, et al · · 2022 · cited 17× · PMID 35892771 · DOI 10.3390/foods11152186
Effect of Olive Pomace Oil on Cardiovascular Health and Associated Pathologies.
González-Rámila S, Sarriá B, Seguido MÁ, García-Cordero J, et al · · 2022 · cited 11× · PMID 36235579 · DOI 10.3390/nu14193927

Verify or expand the search:

Other trials of Olive pomace oil

Trials testing the same drug.

NCT04997122 — Health Effects of Consuming Olive Pomace Oil · NA · completed

Other recruiting trials for Healthy

Currently open trials in the same condition.

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Other Instituto de Ciencia y Tecnología de Alimentos y Nutrición trials

Trials by the same sponsor.

NCT06723886 — Antidiabetic Effect of Olive Pomace Oil · NA · recruiting
NCT05009615 — Efficacy of Hydroxycinnamates and Beta-glucans as a Dietary Tool Against Obesity (OBHEALTH) · NA · completed
NCT04997122 — Health Effects of Consuming Olive Pomace Oil · NA · completed
NCT04321590 — Efficacy of Hydroxycinnamates and Beta-glucans as a Dietary Tool Against obesity_Pilot Study (OBHEALTH_PS) · NA · completed
NCT06729905 — Study of the Effects of Yerba Mate on Cardiometabolic Health · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04998695 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Last refreshed: 16 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04998695.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing