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NCT04996628: P-QST
Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
NA trial testing Quantitative Sensory Test 1 in Chronic Pancreatitis in 150 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | University of Pittsburgh |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 150 |
| Start date | 4 January 2022 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 June 2026 |
| Sites | 3 locations across United States |
Drugs / interventions tested
- Quantitative Sensory Test 1
- Quantitative Sensory Test 2
- Quantitative Sensory Test 3
Conditions studied
- Chronic Pancreatitis — all drugs for Chronic Pancreatitis →
- Chronic Pain — all drugs for Chronic Pain →
Sponsor
University of Pittsburgh
Who can join
18 and older, any sex, with Chronic Pancreatitis or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Abdominal pain in chronic pancreatitis (CP) affects up to 90% of patients during the course of their disease, and response to currently available therapies is suboptimal and unpredictable. The proposed clinical trial will evaluate the predictive capability of Pancreatic Quantitative Sensory Testing (P-QST) - a novel assessment of neurosensory phenotyping- for improvement in pain in patients with CP who are undergoing medically-indicated invasive treatment with endoscopic therapy or surgery.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Pancreatic quantitative sensory testing to predict treatment response of endoscopic therapy or surgery for painful chronic pancreatitis with pancreatic duct obstruction: study protocol for an observational clinical trial.
Phillips AE, Afghani E, Akshintala VS, Benos PY, et al · · 2024 · cited 6× · PMID 38514147 · DOI 10.1136/bmjopen-2023-081505 -
Management of chronic pancreatitis: recent advances and future prospects.
Han C, Lv YW, Hu LH. · · 2024 · cited 5× · PMID 38406795 · DOI 10.1177/17562848241234480
Verify or expand the search:
- PubMed search for NCT04996628
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Quantitative Sensory Test 1
Trials testing the same drug.
- NCT06996535 — Pancreatic Quantitative Sensory Testing (P-QST) · active not recruiting
- NCT03434392 — QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing · NA · recruiting
Other recruiting trials for Chronic Pancreatitis
Currently open trials in the same condition.
- NCT07439757 — AI-Powered Precision Decision-Making for Pancreatic Diseases · recruiting
- NCT06655051 — Single Plastic Stent Vs. Fully Covered Self-Expanding Metal Stent on Benign Biliary Stricture Secondary to Chronic Pancr · NA · recruiting
- NCT06937294 — Metformin in Post Chronic Pancreatitis Diabetes Mellitus · Phase 4 · recruiting
- NCT07109180 — Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOT · NA · recruiting
- NCT06925204 — Natural Course and Therapeutic Effect of Chronic Pancreatitis · recruiting
Other University of Pittsburgh trials
Trials by the same sponsor.
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- NCT06474286 — Prucalopride for Cognitive Functioning in Schizophrenia · NA · not yet recruiting
- NCT06488469 — Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus · NA · not yet recruiting
- NCT06652802 — Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use Disorders · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04996628 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pittsburgh
- Last refreshed: 22 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04996628.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing