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NCT04995900
Heart Matters: The Effectiveness of Heart Health Education in Regions at Highest-risk.
NA trial testing Community education in Acute Coronary Syndrome in 2,240 participants. Completed in 31 March 2023.
31 March 2023
Quick facts
| Lead sponsor | Monash University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 2,240 |
| Start date | 1 February 2022 |
| Primary completion | 31 March 2023 |
| Estimated completion | 31 March 2023 |
| Sites | 1 location across Australia |
Drugs / interventions tested
- Community education
Conditions studied
- Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
- Myocardial Infarction, Acute — all drugs for Myocardial Infarction, Acute →
Sponsor
Monash University
Who can join
18 and older, any sex, with Acute Coronary Syndrome or Myocardial Infarction, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is to evaluate whether providing a targeted heart health education campaign to regions at high risk of heart attacks will improve ACS patient's symptom recognition and response. The intervention will be will be evaluated according to a cluster randomized, stepped wedged design. The clusters are eight local government areas (LGAs) in Victoria, Australia. The main primary outcome will be assessed in consecutive patients presenting to emergency departments from the six LGAs throughout the study period with an ED diagnoses of acute coronary syndrome.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome.
Eastwood K, Howell S, Nehme Z, Finn J, et al · · 2021 · cited 8× · PMID 34663748 · DOI 10.1136/openhrt-2021-001792 -
A protocol for the Heart Matters stepped wedge cluster randomised trial: The effectiveness of heart attack education in regions at highest-risk.
Bray JE, Nehme Z, Finn JC, Kasza J, et al · · 2023 · cited 1× · PMID 37555197 · DOI 10.1016/j.resplu.2023.100431 -
Heart Attack Education and EMS Response in High-Risk, Low EMS Usage Areas: A Stepped-Wedge Cluster-Randomized Trial.
Bray JE, Nehme Z, Finn JC, Kasza J, et al · · 2026 · PMID 42043820 · DOI 10.1001/jamanetworkopen.2026.8823
Verify or expand the search:
- PubMed search for NCT04995900
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Monash University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04995900 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Monash University
- Last refreshed: 15 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04995900.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing