NCT04990401 (BAT) is a NA clinical trial of Behavioral Activation Teletherapy in Depression, sponsored by University of Texas Southwestern Medical Center.

Who is sponsoring NCT04990401?

NCT04990401 is sponsored by University of Texas Southwestern Medical Center.

What drugs are being tested in NCT04990401?

Interventions in NCT04990401: Behavioral Activation Teletherapy.

What condition does NCT04990401 study?

NCT04990401 studies Depression, Depressive Disorder, Depressive Symptoms, Depressive Episode.

Is NCT04990401 still recruiting?

NCT04990401 is currently completed. Last updated 23 December 2025.

Last reviewed 2025-12-23 · How we verify

NCT04990401: BAT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Behavioral Activation Teletherapy to Increase Physical Activity

Completed NA Last updated 23 December 2025

What this trial tests

NA trial testing Behavioral Activation Teletherapy in Depression in 65 participants. Completed in 31 May 2025.

Timeline

31 August 2021

Primary endpoint
30 May 2025

31 May 2025

Quick facts

Lead sponsor	University of Texas Southwestern Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	65
Start date	31 August 2021
Primary completion	30 May 2025
Estimated completion	31 May 2025
Sites	1 location across United States

Drugs / interventions tested

Behavioral Activation Teletherapy

Conditions studied

Depression — all drugs for Depression →
Depressive Disorder — all drugs for Depressive Disorder →
Depressive Symptoms — all drugs for Depressive Symptoms →
Depressive Episode — all drugs for Depressive Episode →

Sponsor

University of Texas Southwestern Medical Center

Who can join

Adults 18 to 64, any sex, with Depression or Depressive Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a pilot study of acceptability, feasibility, and preliminary efficacy of a brief, 10-session Behavioral Activation intervention delivered via teletherapy to increase physical activity and treat depressive symptoms.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pilot evaluation on an adapted tele-behavioral activation to increase physical activity in persons with depression: a single-arm pilot study.
Rethorst CD, Trombello JM, Chen PM, Carmody TJ, et al · · 2024 · cited 1× · PMID 39522018 · DOI 10.1186/s40359-024-02053-5

Verify or expand the search:

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Other University of Texas Southwestern Medical Center trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04990401 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Texas Southwestern Medical Center
Last refreshed: 23 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04990401.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing