Last reviewed · How we verify
NCT04988789
Evaluation of Paclitaxel Coated Balloon in the Treatment of Dialysis Access Dysfunction
trial testing Paclitaxel Drug Coated Balloon in Dialysis Access Malfunction in 500 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Singapore General Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 April 2020 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- Paclitaxel Drug Coated Balloon — full drug profile →
Conditions studied
- Dialysis Access Malfunction — all drugs for Dialysis Access Malfunction →
- Kidney Failure — all drugs for Kidney Failure →
Sponsor
Singapore General Hospital
Who can join
Adults 21 to 99, any sex, with Dialysis Access Malfunction or Kidney Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent studies of paclitaxel DCB in the treatment of stenosis at dialysis vascular access have shown promising results. Paclitaxel, an anti-proliferation drug, is released during balloon inflation and potentially improve primary patency by slowing down NIH effect. However, meta-analysis have suggested that the use of paclitaxel in lower limbs have increased risk of death in patients. The effect of paclitaxel DCB on dialysis access however remains unknown. Hence, we aim to set up a database to track long-term treatment outcomes of patients treated with Paclitaxel DCB at SGH for their stenosed dialysis access
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04988789
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Paclitaxel Drug Coated Balloon
Trials testing the same drug.
- NCT05333640 — A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatm · unknown
Other recruiting trials for Dialysis Access Malfunction
Currently open trials in the same condition.
- NCT06553443 — Randomised Clinical Trial Comparing Drug-coated Balloon to Plain Balloon for All Peripheral AVF Stenosis · Phase 3 · recruiting
Other Singapore General Hospital trials
Trials by the same sponsor.
- NCT07452159 — Diabetes In Asians at Risk in Youth · not yet recruiting
- NCT07527247 — Improving Vaccine Protection for Older Adults · Phase 2 · recruiting
- NCT07533188 — Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomize · NA · recruiting
- NCT07042061 — Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore. · NA · not yet recruiting
- NCT07099040 — Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04988789 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Singapore General Hospital
- Last refreshed: 4 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04988789.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing