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NCT04986969: COMBAT-DS
Online Cognitive Behavioral Therapy for Depressive Symptoms in Rural Patients with Cardiac Disease
NA trial testing Online cognitive behavioral therapy in Depressive Symptoms in 444 participants. Completed in 1 August 2024.
1 August 2024
Quick facts
| Lead sponsor | Debra Moser |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 444 |
| Start date | 15 April 2021 |
| Primary completion | 1 August 2024 |
| Estimated completion | 1 August 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Online cognitive behavioral therapy
Conditions studied
- Depressive Symptoms — all drugs for Depressive Symptoms →
- Heart Diseases — all drugs for Heart Diseases →
Sponsor
Debra Moser
Who can join
Adults 21 to 110, any sex, with Depressive Symptoms or Heart Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Individuals with heart disease and depressive symptoms suffer from higher death rates, higher rates of acute cardiac events (such as heart attacks), and faster progression of heart disease compared to those with heart disease who do not have depressive symptoms, and these problems are much worse in rural people. Unfortunately, rural people with heart disease and depressive symptoms do not receive needed therapy for depressive symptoms because of lack of mental health providers in rural areas, worries about stigma, and difficulty accessing mental health care because of multiple barriers to traveling to get care. To overcome these barriers, the investigators will compare the impact of two types of online cognitive behavioral therapy (video-conferenced face-to-face versus self-administered internet-based) and usual care on depressive symptoms to provide patients and healthcare providers with needed information about which is more effective and to increase the number of patients adequately treated.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation.
Ski CF, Taylor RS, McGuigan K, Long L, et al · · 2024 · cited 30× · PMID 38577875 · DOI 10.1002/14651858.cd013508.pub3
Verify or expand the search:
- PubMed search for NCT04986969
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Online cognitive behavioral therapy
Trials testing the same drug.
- NCT05585827 — Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease · NA · completed
- NCT04995913 — Online Cognitive Behavioral Intervention Program for Hong Kong People With Social Anxiety Disorder · NA · unknown
Other recruiting trials for Depressive Symptoms
Currently open trials in the same condition.
- NCT07299903 — IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression · NA · recruiting
- NCT07413692 — BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Urinary Incontinence in Postpartum and E · NA · recruiting
- NCT07413705 — BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimenopausal and · NA · recruiting
- NCT07241325 — Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cross-Section · recruiting
- NCT07216326 — Our Voices Matter: Intervention for Depression in Youth · NA · recruiting
Other Debra Moser trials
Trials by the same sponsor.
- NCT04994782 — GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers · NA · completed
- NCT03068390 — Rural Intervention for Caregivers' Heart Health · NA · completed
- NCT01884246 — Improving Heart Health in Appalachia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04986969 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Debra Moser
- Last refreshed: 15 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04986969.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing