NCT04985396

Platelet Rich Plasma Injection Compared With Steroid Injection for the Treatment of Plantar Fasciitis

Completed NA Last updated 18 May 2022

What this trial tests

NA trial testing Platelet Rich Plasma (PRP) group in Plantar Fasciitis in 78 participants. Completed in 1 February 2022.

Timeline

25 July 2021

Primary endpoint
26 January 2022

1 February 2022

Quick facts

Lead sponsor	Armed Police Force Hospital, Nepal
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	78
Start date	25 July 2021
Primary completion	26 January 2022
Estimated completion	1 February 2022
Sites	1 location across Nepal

Drugs / interventions tested

• Platelet Rich Plasma (PRP) group

Conditions studied

• Plantar Fasciitis — all drugs for Plantar Fasciitis →
• Steroid — all drugs for Steroid →
• Platelet-rich Plasma (PRP) — all drugs for Platelet-rich Plasma (PRP) →

Sponsor

Armed Police Force Hospital, Nepal

Who can join

Adults 18 to 60, any sex, with Plantar Fasciitis or Steroid. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Plantar fasciitis (PF) is the one of the most common orthopaedic problem resulting in heel pain. Previous evidence suggests that Platelet Rich Plasma (PRP) injection has better outcome in the long run as compared to the local steroid injection (SI). Although over the past many years, steroid injection was considered as the choice of treatment after the failure of conservative treatment methods, PRP therapy has shown promising results in the treatment of plantar fasciitis now-a-days. The aim of this study is to assess the effect of PRP injection compared with Steroid injection in the treatment of Plantar Fasciitis.

A hospital-based randomized clinical trial study will be carried out to compare the efficacy of the therapeutic effect between steroid injection and Platelet Rich Plasma injection in plantar fasciitis. A representative sample size of 78 patients aged 18 years to 60 years suffering from plantar fasciitis with failed conservative treatment will be intervened. The American Orthopedic Foot and Ankle Society (AOFAS) and the visual analog scale (VAS) scoring system will be recorded pre- and post-injection phases at 3 months and 6 months period. Statistical analyses will be performed using independent t-test and Mann Whitney U test to compare between the two means. The outcome of this study will help to guide the physicians to choose the better therapeutic approach among the patients suffering from plantar fasciitis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effect of platelet-rich plasma versus steroid injection in plantar fasciitis: a randomized clinical trial.
   Sharma R, Chaudhary NK, Karki M, Sunuwar DR, et al · · 2023 · cited 18× · PMID 36882804 · DOI 10.1186/s12891-023-06277-1