Brain Mechanisms Supporting Cannabis-induced Pain Relief

NCT04982965 EARLY_PHASE1 RECRUITING

The American Academy of Pain Medicine has labeled pain as a "silent epidemic" due to its staggering costs to society (over $500 billion/year) and widespread prevalence (affects over 100 million Americans). Thus, it is imperative to test and validate cost-effective pain therapies. To this extent, cannabis is characterized as one of the most promising therapies to treat a wide spectrum of pain conditions. However, the clinical applicability of cannabis-based pain therapies has been limited due to lacking mechanistic characterization in human-focused studies. Of critical importance, the neural mechanisms supporting cannabis induced pain relief remain unknown. The primary objective of the proposed pilot study is to identify the brain mechanisms supporting the direct alleviation of acutely evoked pain through vaporized cannabis.

Details

Lead sponsor	University of California, San Diego
Phase	EARLY_PHASE1
Status	RECRUITING
Enrolment	100
Start date	Fri May 07 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Mar 15 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Pain, Acute

Interventions

• Active Cannabis
• Placebo Cannabis

Countries

United States