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NCT04980560
Gut Microbiota Profile and Its Impact on Immunity Status in COVID-19 Vaccinated Cohorts
trial in COVID-19 Vaccination in 215 participants. Participants enrolled and being followed up; not accepting new ones.
17 June 2024
Quick facts
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 215 |
| Start date | 14 May 2021 |
| Primary completion | 17 June 2024 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Hong Kong |
Conditions studied
- COVID-19 Vaccination — all drugs for COVID-19 Vaccination →
- Gut Microbiota — all drugs for Gut Microbiota →
Sponsor
Chinese University of Hong Kong
Who can join
18 and older, any sex, with COVID-19 Vaccination or Gut Microbiota. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to examine the association between gut microbiota composition and the magnitude and duration of immune response in subjects who have received different COVID-19 vaccines in Hong Kong and to identify the differences compared to those COVID-19 recovered subjects.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
The intestinal microbiota and improving the efficacy of COVID-19 vaccinations.
Chen J, Vitetta L, Henson JD, Hall S. · · 2021 · cited 23× · PMID 34777578 · DOI 10.1016/j.jff.2021.104850 -
Targeting the Gut Microbiota in Coronavirus Disease 2019: Hype or Hope?
Lau HC, Ng SC, Yu J. · · 2022 · cited 16× · PMID 34508775 · DOI 10.1053/j.gastro.2021.09.009 -
A comprehensive perspective on the interaction between gut microbiota and COVID-19 vaccines.
Hong M, Lan T, Li Q, Li B, et al · · 2023 · cited 13× · PMID 37431857 · DOI 10.1080/19490976.2023.2233146 -
Modulated Gut Microbiota for Potential COVID-19 Prevention and Treatment.
Zhao S, Feng P, Meng W, Jin W, et al · · 2022 · cited 12× · PMID 35308540 · DOI 10.3389/fmed.2022.811176
Verify or expand the search:
- PubMed search for NCT04980560
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Chinese University of Hong Kong trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04980560 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
- Last refreshed: 26 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04980560.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing