NCT04980105 is a Phase 3 clinical trial of Platelet-rich plasma in Osteoarthritis, Knee, sponsored by University of Wasit.

Who is sponsoring NCT04980105?

NCT04980105 is sponsored by University of Wasit.

What drugs are being tested in NCT04980105?

Interventions in NCT04980105: Platelet-rich plasma, Hyaluronic acid, Methylprednisolone acetate injectable suspension (DEPO-MEDROL®).

What condition does NCT04980105 study?

NCT04980105 studies Osteoarthritis, Knee.

Is NCT04980105 still recruiting?

NCT04980105 is currently status unknown. Last updated 28 July 2021.

Last reviewed 2021-07-28 · How we verify

NCT04980105

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intra-articular Injections of Platelet-rich Plasma, Hyaluronic Acid, or Corticosteroids for Knee Osteoarthritis

Status unknown Phase 3 Last updated 28 July 2021

What this trial tests

Phase 3 trial testing Platelet-rich plasma in Osteoarthritis, Knee in 150 participants. Status unknown.

Timeline

2 March 2020

Primary endpoint
1 September 2021

1 October 2021

Quick facts

Lead sponsor	University of Wasit
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	150
Start date	2 March 2020
Primary completion	1 September 2021
Estimated completion	1 October 2021
Sites	1 location across Iraq

Drugs / interventions tested

Platelet-rich plasma
Hyaluronic acid (HYALURONIC ACID) — full drug profile →
Methylprednisolone acetate injectable suspension (DEPO-MEDROL®) — full drug profile →

Conditions studied

Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →

Sponsor

University of Wasit

Who can join

Adults 35 to 65, any sex, with Osteoarthritis, Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To assess if there are any differences among platelet-rich plasma, hyaluronic acid, and corticosteroid knee intra-articular injection regarding function and pain.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Current Status of Clinical Trials on Biologics for Cartilage Repair and Osteoarthritis Treatment: An Analysis of ClinicalTrials.gov Data.
Zhang Z, Schon L. · · 2022 · cited 21× · PMID 35546280 · DOI 10.1177/19476035221093065

Verify or expand the search:

Other trials of Platelet-rich plasma

Trials testing the same drug.

NCT07103551 — Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner · Phase 3 · not yet recruiting
NCT06372600 — Effect of Extracorporeal Shock Wave Combined With Autologous Platelet-rich Plasma Injection on Rotator Cuff Calcific Ten · NA · not yet recruiting
NCT06442319 — The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction. · NA · recruiting
NCT05329116 — Efficacy of Mesotherapy Added to Intra-articular Platelet-rich Plasma (PRP) in Patients With Knee Osteoarthritis · NA · unknown
NCT05214924 — Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management · Phase 2, PHASE3 · enrolling by invitation

Other recruiting trials for Osteoarthritis, Knee

Currently open trials in the same condition.

NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT06488144 — Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans · Phase 3 · recruiting
NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT07514598 — Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA) · NA · active not recruiting
NCT07058623 — Nurse-Led Telehealth vs In-Person Follow-Up After Total Knee Replacement · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04980105 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Wasit
Last refreshed: 28 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04980105.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing