NCT04976231 is a clinical trial in MPS II, sponsored by Duke University.

Who is sponsoring NCT04976231?

NCT04976231 is sponsored by Duke University.

What condition does NCT04976231 study?

NCT04976231 studies MPS II, Mucopolysaccharidosis II, Hunter Syndrome.

Is NCT04976231 still recruiting?

NCT04976231 is currently terminated. Last updated 19 September 2024.

Last reviewed 2024-09-19 · How we verify

NCT04976231

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MPS II Immunophenotyping

Terminated Last updated 19 September 2024

What this trial tests

trial in MPS II in 6 participants. Terminated before completion.

Timeline

1 April 2022

Primary endpoint
26 April 2024

26 April 2024

Quick facts

Lead sponsor	Duke University
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	6
Start date	1 April 2022
Primary completion	26 April 2024
Estimated completion	26 April 2024
Sites	1 location across United States

Conditions studied

MPS II — all drugs for MPS II →
Mucopolysaccharidosis II — all drugs for Mucopolysaccharidosis II →
Hunter Syndrome — all drugs for Hunter Syndrome →

Sponsor

Duke University

Who can join

Eligibility, any sex, with MPS II or Mucopolysaccharidosis II. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to investigate how participant's body's immune system responds to idursulfase, an enzyme replacement therapy (ERT) and find out which types of immune cells are involved in causing untoward responses to the ERT so that the investigators can relate the level of immune response to the treatment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for MPS II

Currently open trials in the same condition.

NCT04532047 — PEARL (PrEnAtal Enzyme Replacement Therapy for Lysosomal Storage Disorders) · Phase 1 · recruiting

Other Duke University trials

Trials by the same sponsor.

NCT07216456 — Vaginal Dilator Therapy After Pelvic Radiation · NA · not yet recruiting
NCT07519317 — Dosing and Deployment Trial: A Home-based Optokinetic Treatment · NA · not yet recruiting
NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07216963 — The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · NA · not yet recruiting
NCT07459218 — IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04976231 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 19 September 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04976231.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing