NCT04975620 is a NA clinical trial of Fine needle biopsy in Pancreatic Neoplasms, sponsored by University of Tehran.

Who is sponsoring NCT04975620?

NCT04975620 is sponsored by University of Tehran.

What drugs are being tested in NCT04975620?

Interventions in NCT04975620: Fine needle biopsy.

What condition does NCT04975620 study?

NCT04975620 studies Pancreatic Neoplasms.

Is NCT04975620 still recruiting?

NCT04975620 is currently completed. Last updated 16 May 2023.

Last reviewed 2023-05-16 · How we verify

NCT04975620

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of Two Types of Biopsy Needles for EUS-FNB in Solid Pancreatobiliary Mass Lesions

Completed NA Last updated 16 May 2023

What this trial tests

NA trial testing Fine needle biopsy in Pancreatic Neoplasms in 114 participants. Completed in 30 June 2022.

Timeline

1 August 2021

Primary endpoint
15 June 2022

30 June 2022

Quick facts

Lead sponsor	University of Tehran
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	114
Start date	1 August 2021
Primary completion	15 June 2022
Estimated completion	30 June 2022
Sites	1 location across Iran

Drugs / interventions tested

Fine needle biopsy

Conditions studied

Pancreatic Neoplasms — all drugs for Pancreatic Neoplasms →

Sponsor

University of Tehran

Who can join

18 and older, any sex, with Pancreatic Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

EUS-guided tissue acquisition is an established modality to diagnose malignancies of the pancreas and extrahepatic bile ducts. In the recent years fine needle biopsy (FNB) needles have largely replaced fine needle aspiration (FNA) for EUS-guided tissue acquisition. The Acquire FNB needle is a Franseen needle which has three symmetric cutting edges to obtain core tissue specimens. The Trident FNB needle has been recently introduced to the market for EUS-guided tissue acquisition. It has a multi-blade three-prong tip which one of the tips is longer than the other two. The aim of this study is to prospectively compare these two types of needle in term of diagnostic accuracy, and safety profile.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparing per-pass performance of 2 types of needles for EUS-guided fine-needle biopsy sampling of pancreatobiliary masses in a randomized trial.
Mohamadnejad M, Mirzaie V, Sotoudeh M, Nikmanesh A, et al · · 2023 · cited 8× · PMID 37098399 · DOI 10.1016/j.gie.2023.04.2070

Verify or expand the search:

Other recruiting trials for Pancreatic Neoplasms

Currently open trials in the same condition.

NCT07504471 — Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhib · Phase 2 · recruiting
NCT07139236 — Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD · recruiting
NCT06885697 — Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Includi · Phase 1 · recruiting
NCT06939023 — Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3) · NA · recruiting
NCT06953193 — Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia · NA · recruiting

Other University of Tehran trials

Trials by the same sponsor.

NCT07168863 — EUS-guided FNB-induced PANCREatitis Assessment · recruiting
NCT05530772 — Immediate vs. On-demand Endoscopic Necrosectomy in Infected Walled-off Pancreatic Necrosis · NA · completed
NCT05569902 — tACS Improves Memory in Elders With Subjective Memory Complaints · NA · completed
NCT06030024 — Efficacy of Repetitive Transcranial Magnetic Stimulation in Adult Attention Deficit Disorder · NA · completed
NCT03468686 — The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04975620 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Tehran
Last refreshed: 16 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04975620.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing