NCT04972526 (rTEECoRe) is a clinical trial in Cardiac Arrest, sponsored by University of Pennsylvania.

Who is sponsoring NCT04972526?

NCT04972526 is sponsored by University of Pennsylvania.

What condition does NCT04972526 study?

NCT04972526 studies Cardiac Arrest, Cardiac Arrest Circulatory, Cardiac Arrest, Out-Of-Hospital, Shock, Hemodynamic Instability.

Is NCT04972526 still recruiting?

NCT04972526 is currently recruiting now. Last updated 14 January 2026.

Last reviewed 2026-01-14 · How we verify

NCT04972526: rTEECoRe

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Resuscitative TEE Collaborative Registry

Recruiting now Last updated 14 January 2026

What this trial tests

trial in Cardiac Arrest in 1,000 participants. Currently enrolling.

Timeline

1 December 2020

Primary endpoint
15 December 2027

15 December 2027

Quick facts

Lead sponsor	University of Pennsylvania
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 December 2020
Primary completion	15 December 2027
Estimated completion	15 December 2027
Sites	1 location across United States

Conditions studied

Cardiac Arrest — all drugs for Cardiac Arrest →
Cardiac Arrest Circulatory — all drugs for Cardiac Arrest Circulatory →
Cardiac Arrest, Out-Of-Hospital — all drugs for Cardiac Arrest, Out-Of-Hospital →
Shock — all drugs for Shock →

Sponsor

University of Pennsylvania

Who can join

18 and older, any sex, with Cardiac Arrest or Cardiac Arrest Circulatory. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The general objective of this study is to evaluate the clinical impact and safety of focused, point-of-care transesophageal echocardiography (TEE) used during the evaluation of critically-ill patients in the emergency and intensive care settings. The target population for this study are critically-ill patients over the age of 18 who as part of their routine clinical care are receiving a focused TEE. The primary objective of this study is to determine the clinical impact and safety of TEE performed during the evaluation of critically-ill patients in the emergency department and intensive care settings. The secondary objective(s) of this study are to characterize the use of this imaging modality in the subsets of critically-ill patients in shock and cardiac arrest; including but not limited to; description of the frequency of studies, clinical indications, clinician characteristics, echocardiography findings, timing of studies, procedure-related complications and patient outcomes.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Development and Implementation of a Multicenter Registry for Resuscitation-Focused Transesophageal Echocardiography.
Teran F, Owyang CG, Wray TC, Hipskind JE, et al · · 2025 · cited 5× · PMID 39412464 · DOI 10.1016/j.annemergmed.2024.08.004
Resuscitative Transesophageal Echocardiography in Critical Care.
Teran F, Diederich T, Owyang CG, Stancati JA, et al · · 2025 · cited 1× · PMID 40096050 · DOI 10.1177/08850666241272065

Verify or expand the search:

Other recruiting trials for Cardiac Arrest

Currently open trials in the same condition.

NCT07239206 — Serious Game for Improving Targeted Temperature Management Knowledge and Situational Awareness in Critical Care Nurses · NA · recruiting
NCT06780722 — Study of the Occurrence of Cardiocirculatory Arrest as a Function of the Level of Hypoxemia During a Maastricht 3 Proced · recruiting
NCT06405581 — The Impact of Frailty on Cardiopulmonary Resuscitation Adverse Outcomes in Patients Requiring Code Blue Activation · recruiting
NCT06511999 — Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest · recruiting
NCT07113769 — Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation · recruiting

Other University of Pennsylvania trials

Trials by the same sponsor.

NCT06081153 — Mechanistic Clinical Trial of PCSK9 Inhibition for AAA · EARLY_PHASE1 · not yet recruiting
NCT07415772 — Effect of cTBS on Startle and TMS-evoked BOLD · NA · not yet recruiting
NCT07489430 — DaxibotulinumtoxinA for Blepharospasm · Phase 2 · not yet recruiting
NCT07463131 — Negative Income Tax Trial · NA · not yet recruiting
NCT06645769 — Na-Phenylbutyrate VAscular Trial · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04972526 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pennsylvania
Last refreshed: 14 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04972526.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing