Last reviewed · How we verify
NCT04972266
The EU Hyprotect Registry
trial testing AcumenTM Hypotension Prediction Index software in Hemodynamic Monitoring in 702 participants. Completed in 1 September 2022.
1 September 2022
Quick facts
| Lead sponsor | Edwards Lifesciences |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 702 |
| Start date | 28 September 2021 |
| Primary completion | 1 September 2022 |
| Estimated completion | 1 September 2022 |
| Sites | 12 locations across France, Italy, United Kingdom, Germany, Spain |
Drugs / interventions tested
- AcumenTM Hypotension Prediction Index software
Conditions studied
- Hemodynamic Monitoring — all drugs for Hemodynamic Monitoring →
Sponsor
Edwards Lifesciences — full company profile →
Who can join
18 and older, any sex, with Hemodynamic Monitoring. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Intraoperative hypotension when using hypotension prediction index software during major noncardiac surgery: a European multicentre prospective observational registry (EU HYPROTECT).
Kouz K, Monge García MI, Cerutti E, Lisanti I, et al · · 2023 · cited 39× · PMID 37588176 · DOI 10.1016/j.bjao.2023.100140 -
Hypotension Prediction Index Software to Prevent Intraoperative Hypotension during Major Non-Cardiac Surgery: Protocol for a European Multicenter Prospective Observational Registry (EU-HYPROTECT).
Monge García MI, García-López D, Gayat É, Sander M, et al · · 2022 · cited 12× · PMID 36233455 · DOI 10.3390/jcm11195585 -
Association of intraoperative hypotension and acute kidney injury in noncardiac surgery patients: a post hoc secondary analysis of the EU HYPROTECT registry.
Runge J, Grundmann CD, Mucha C, Denz R, et al · · 2026 · cited 4× · PMID 40676457 · DOI 10.1007/s10877-025-01329-4
Verify or expand the search:
- PubMed search for NCT04972266
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hemodynamic Monitoring
Currently open trials in the same condition.
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- NCT07062744 — The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock · NA · recruiting
- NCT06918301 — Comparison of Cardiac Index and Stroke-volume-index Measured by Pulmonary Artery Catheter, FloTrac® and Argos® in Cardia · recruiting
- NCT07270341 — Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anest · recruiting
- NCT04281771 — Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI · NA · active not recruiting
Other Edwards Lifesciences trials
Trials by the same sponsor.
- NCT07317648 — ClearSight NextGen1 Study · NA · completed
- NCT06833476 — TTVR STRONG Under Coverage With Evidence Development (CED) Study · recruiting
- NCT06569602 — Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU) · recruiting
- NCT06834516 — ClearSight Baby Cuff · completed
- NCT05957406 — SMART TRENDS Study · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04972266 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Edwards Lifesciences
- Last refreshed: 4 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04972266.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing