Overall Comfort was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Overall Comfort" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
45
Verofilcon A
32
Very Good
Group
Value
95% CI
Senofilcon A (C3)
20
Verofilcon A
23
Good
Group
Value
95% CI
Senofilcon A (C3)
5
Verofilcon A
9
Fair
Group
Value
95% CI
Senofilcon A (C3)
2
Verofilcon A
7
Poor
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
1
End of Day Comfort (Phase I)Primary· 1-Week Follow-up
End of day Comfort was assessed using the individual questionnaire item "How would you rate the study contact lenses on: comfort at the end of the day" with aa 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
29
Verofilcon A
25
Very Good
Group
Value
95% CI
Senofilcon A (C3)
28
Verofilcon A
17
Good
Group
Value
95% CI
Senofilcon A (C3)
9
Verofilcon A
16
Fair
Group
Value
95% CI
Senofilcon A (C3)
4
Verofilcon A
10
Poor
Group
Value
95% CI
Senofilcon A (C3)
2
Verofilcon A
4
End of Day Dryness (Phase I)Primary· 1-Week Follow-up
End of day Dryness was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Keeping your eyes from feeling dry at the end of the day" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
26
Verofilcon A
22
Very Good
Group
Value
95% CI
Senofilcon A (C3)
28
Verofilcon A
20
Good
Group
Value
95% CI
Senofilcon A (C3)
9
Verofilcon A
12
Fair
Group
Value
95% CI
Senofilcon A (C3)
6
Verofilcon A
12
Poor
Group
Value
95% CI
Senofilcon A (C3)
3
Verofilcon A
6
End of Day Comfort (Phase II)Primary· 1-Week Follow-up
End of day Comfort was assessed using the individual questionnaire item "How would you rate the study contact lenses on: comfort at the end of the day" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
89
Verofilcon A
65
Very Good
Group
Value
95% CI
Senofilcon A (C3)
63
Verofilcon A
59
Good
Group
Value
95% CI
Senofilcon A (C3)
24
Verofilcon A
39
Fair
Group
Value
95% CI
Senofilcon A (C3)
26
Verofilcon A
34
Poor
Group
Value
95% CI
Senofilcon A (C3)
8
Verofilcon A
13
End of Day Dryness (Phase II)Primary· 1-Week Follow-up
End of day Dryness was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Keeping your eyes from feeling dry at the end of the day" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Overall Comfort was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Overall Comfort" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
127
Verofilcon A
104
Very Good
Group
Value
95% CI
Senofilcon A (C3)
44
Verofilcon A
59
Good
Group
Value
95% CI
Senofilcon A (C3)
28
Verofilcon A
30
Fair
Group
Value
95% CI
Senofilcon A (C3)
11
Verofilcon A
13
Poor
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
3
Not Applicable
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
1
Comfort Throughout the Day (Phase II)Secondary· 1-Week Follow-up
Comfort Throughout the Day was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Keeping your eyes feeling comfortable from morning to night" with a 6-point Excellence Response Set of 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Excellent
Group
Value
95% CI
Senofilcon A (C3)
96
Verofilcon A
76
Very Good
Group
Value
95% CI
Senofilcon A (C3)
55
Verofilcon A
56
Good
Group
Value
95% CI
Senofilcon A (C3)
29
Verofilcon A
45
Fair
Group
Value
95% CI
Senofilcon A (C3)
26
Verofilcon A
25
Poor
Group
Value
95% CI
Senofilcon A (C3)
4
Verofilcon A
8
Comfort While Using Digital Devices (Phase II)Secondary· 1-Week Follow-up
Comfort while Using Digital Devices was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Remaining comfortable while using computer screens and other digital devices (phones, tablets)" with a 6-point Excellence Response Set of 0: Not Applicable, 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Not Applicable
Group
Value
95% CI
Senofilcon A (C3)
1
Verofilcon A
2
Excellent
Group
Value
95% CI
Senofilcon A (C3)
111
Verofilcon A
90
Very Good
Group
Value
95% CI
Senofilcon A (C3)
46
Verofilcon A
61
Good
Group
Value
95% CI
Senofilcon A (C3)
33
Verofilcon A
31
Fair
Group
Value
95% CI
Senofilcon A (C3)
17
Verofilcon A
22
Poor
Group
Value
95% CI
Senofilcon A (C3)
2
Verofilcon A
4
Dryness While Using Digital Devices (Phase II)Secondary· 1-Week Follow-up
Dryness while using Digital Devices was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Keeping your eyes from feeling dry while using computer screens and other digital devices (phones, tablets)." with a 6-point Excellence Response Set of 0: Not Applicable, 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Not Applicable
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
2
Excellent
Group
Value
95% CI
Senofilcon A (C3)
102
Verofilcon A
79
Very Good
Group
Value
95% CI
Senofilcon A (C3)
55
Verofilcon A
63
Good
Group
Value
95% CI
Senofilcon A (C3)
25
Verofilcon A
31
Fair
Group
Value
95% CI
Senofilcon A (C3)
22
Verofilcon A
31
Poor
Group
Value
95% CI
Senofilcon A (C3)
6
Verofilcon A
4
Lens Awareness Upon Insertion (Phase II)Secondary· 1-Minute Post lens fitting
Lens Awareness Upon Insertion was assessed using the individual questionnaire item "I lost awareness of these lenses shortly after inserting them (within one minute)" with a 5-point Agreement Response Set of 1: Strongly Disagree, 2: Disagree, 3: Neither Agree nor Disagree, 4: Agree and 5: Strongly Agree. Subject responses are reported by lens using frequencies.
Strongly Disagree
Group
Value
95% CI
Senofilcon A (C3)
16
Verofilcon A
16
Disagree
Group
Value
95% CI
Senofilcon A (C3)
6
Verofilcon A
13
Neither Agree nor Disagree
Group
Value
95% CI
Senofilcon A (C3)
7
Verofilcon A
8
Agree
Group
Value
95% CI
Senofilcon A (C3)
65
Verofilcon A
71
Strongly Agree
Group
Value
95% CI
Senofilcon A (C3)
126
Verofilcon A
113
Comfort Upon Insertion (Phase II)Secondary· 1-Minute Post lens fitting
Comfort Upon Insertion was assessed using the individual questionnaire item "These lenses were comfortable shortly after inserting them (within one minute)" with a 5-point Agreement Response Set of 1: Strongly Disagree, 2: Disagree, 3: Neither Agree nor Disagree, 4: Agree and 5: Strongly Agree. Subject responses are reported by lens using frequencies.
Strongly Disagree
Group
Value
95% CI
Senofilcon A (C3)
2
Verofilcon A
6
Disagree
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
3
Neither Agree nor Disagree
Group
Value
95% CI
Senofilcon A (C3)
4
Verofilcon A
9
Agree
Group
Value
95% CI
Senofilcon A (C3)
61
Verofilcon A
64
Strongly Agree
Group
Value
95% CI
Senofilcon A (C3)
153
Verofilcon A
139
Overall Ease of Handling (Phase II)Secondary· 1-Week Follow-up
Overall Ease of Handling was assessed using the individual questionnaire item "How would you rate the study contact lenses on: Overall ease of handling the lenses (putting them on and taking them off)." with a 6-point Excellence Response Set of 0: Not Applicable, 1: Excellent, 2: Very Good, 3: Good, 4: Fair and 5: Poor. Subject responses are reported by lens using frequencies.
Not Applicable
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
2
Excellent
Group
Value
95% CI
Senofilcon A (C3)
140
Verofilcon A
112
Very Good
Group
Value
95% CI
Senofilcon A (C3)
36
Verofilcon A
40
Good
Group
Value
95% CI
Senofilcon A (C3)
23
Verofilcon A
32
Fair
Group
Value
95% CI
Senofilcon A (C3)
11
Verofilcon A
16
Poor
Group
Value
95% CI
Senofilcon A (C3)
0
Verofilcon A
8
Sponsor's own description
This study is a 2-phase adaptive approach utilizing a 2×2 crossover design. The study lenses will be worn in a bilateral fashion for a period of approximately 1-week each.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
NCT05021081 — Visual Performance of Senofilcon A With and Without a New UV/HEV-filter
· NA
· completed
NCT04849780 — Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens
· NA
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Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Vision Care, Inc.
Last refreshed: 22 December 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04968925.