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NCT04964024

SaRS-Cov-2 Antibodies Following Exposure to Coronavirus Disease 2019 (COVID-19) and/or Vaccination in Nursing Homes

Completed Last updated 19 July 2022
What this trial tests

trial testing SARS-CoV-2 antibodies in COVID-19 Infection in 1,293 participants. Completed in 15 May 2022.

Timeline
15 July 2021
Primary endpoint
15 May 2022
15 May 2022

Quick facts

Lead sponsorCentral Hospital, Nancy, France
StatusCompleted
Study typeOBSERVATIONAL
Enrollment1,293
Start date15 July 2021
Primary completion15 May 2022
Estimated completion15 May 2022
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Central Hospital, Nancy, France

Who can join

Adults 20 to 110, any sex, with COVID-19 Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Presence of SaRS-Cov-2 antibodies following exposure to Coronavirus Disease 2019 (COVID-19) and/or vaccination is a major indicator of immunization. Few data exit about serology response in nursing homes (NHs), i.e. in the most vulnerable population for developing severe forms of the disease. Residents and health professionals in 9 nursing homes (NHs) with SaRS-Cov-2 antibodies detection after exposure (either COVID-19 or vaccine) All biological tests were performed in the frame of the standard care of residents and health professionals and all participants did not express opposition for using anonymously their data for the purpose of this academic analysis. In addition all Directors and Physicians of these NHs accepted to participate in this study

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Anti-spike IgG antibody kinetics following the second and third doses of BNT162b2 vaccine in nursing home residents.
    Jeulin H, Labat C, Duarte K, Toupance S, et al · · 2022 · cited 19× · PMID 35484977 · DOI 10.1111/jgs.17837
  2. Risk of SARS-CoV-2 Infection in Nursing Home Residents According to COVID History and IgG Anti-Spike Antibody Levels.
    Jeulin H, Labat C, Benetos A. · · 2023 · PMID 36463969 · DOI 10.1016/j.jamda.2022.11.004
  3. History of SARS-CoV-2 infection, anti-spike IgG antibody kinetics and neutralization capacities following the second and third dose of BNT162b2 vaccine in nursing home residents
    Jeulin H, Labat C, Duarte K, Toupance S, et al · · 2022 · DOI 10.1101/2022.02.07.22270557
  4. Comparative analysis of post-vaccination anti-spike IgG antibodies in old Nursing Home Residents and in middle-aged Healthcare workers
    Jeulin H, Craus D, Labat C, Benetos A. · · 2021 · DOI 10.1101/2021.08.03.21261014

Verify or expand the search:

Other recruiting trials for COVID-19 Infection

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Other Central Hospital, Nancy, France trials

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Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing