NCT04961255 is a clinical trial in Post-COVID-19, sponsored by University of Brasilia.

Who is sponsoring NCT04961255?

NCT04961255 is sponsored by University of Brasilia.

What condition does NCT04961255 study?

NCT04961255 studies Post-COVID-19, Healthy Participants.

Is NCT04961255 still recruiting?

NCT04961255 is currently status unknown. Last updated 5 December 2023.

Last reviewed 2023-12-05 · How we verify

NCT04961255

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Post-COVID-19 on Quadriceps Femoral Muscle-tendon Unit

Status unknown Last updated 5 December 2023

What this trial tests

trial in Post-COVID-19 in 90 participants. Status unknown.

Timeline

24 August 2021

Primary endpoint
30 August 2024

30 December 2024

Quick facts

Lead sponsor	University of Brasilia
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	90
Start date	24 August 2021
Primary completion	30 August 2024
Estimated completion	30 December 2024
Sites	1 location across Brazil

Conditions studied

Post-COVID-19 — all drugs for Post-COVID-19 →
Healthy Participants — all drugs for Healthy Participants →

Sponsor

University of Brasilia

Who can join

Adults 18 to 80, any sex, with Post-COVID-19 or Healthy Participants. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The physiological/biomechanical characteristics related to muscle and tendon architecture and their possible relationship with the loss of muscle strength and fatigue in patients who were infected with COVID-19 are totally unknown. The aim of this study is to evaluate inflammatory markers, the isometric maximum voluntary force of the knee extensor torque, muscle fatigue, neuromuscular adaptations, muscle architecture, tendinous properties of quadriceps components, oxygen extraction, and body composition in participants after diagnosis with Covid-19 who had moderate and severe levels of involvement compared to a healthy control group.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Intra- and Inter-Rater Reliability and Agreement of Ultrasound Imaging of Muscle Architecture and Patellar Tendon in Post-COVID-19 Patients Who Had Experienced Moderate or Severe COVID-19 Infection.
de Jesus Ferreira LG, de Almeida Ventura Á, da Silva Almeida I, Mansur H, et al · · 2022 · cited 5× · PMID 36498509 · DOI 10.3390/jcm11236934
Fatigue and neuromuscular function in long COVID: A one-year follow-up study.
Almeida IDS, Ferreira LGJ, Vaz MA, Cipriano Junior G, et al · · 2025 · cited 1× · PMID 40991619 · DOI 10.1371/journal.pone.0332242
Impact of COVID-19 on patellar tendon properties over the first year after infection.
de Jesus Ferreira LG, da Silva Almeida I, Costa RR, Roriz GV, et al · · 2026 · PMID 41501086 · DOI 10.1038/s41598-025-06879-w
Persistent neuromuscular disorders associated with changes in tibialis anterior and gastrocnemius lateralis muscle architecture in long-covid: an observational longitudinal study.
da Silva Almeida I, de Jesus Ferreira LG, Cipriano G, Costa RR, et al · · 2025 · PMID 41038893 · DOI 10.1038/s41598-025-17126-7
Long COVID-19 alters muscle architecture and muscle-tendon force transmission: a one-year longitudinal study.
Ferreira LGJ, da Silva Almeida I, Costa RR, Roriz GV, et al · · 2025 · PMID 40926885 · DOI 10.3389/fphys.2025.1641046

Verify or expand the search:

Other University of Brasilia trials

Trials by the same sponsor.

NCT07453485 — Immediate Effects of Neuromuscular Electrical Stimulation on Pain and Function in Achilles Tendon Disorders · NA · recruiting
NCT07515989 — Accuracy of the Polymerase Chain Reaction of Ulnar Perineural Subcutaneous Aspirate Guided by Ultrasound for the Diagnos · NA · recruiting
NCT06651099 — Trial-based Economic Evaluation of a Mobile Health Intervention for Individuals With Chronic Non-specific Low Back Pain · NA · recruiting
NCT06318728 — Musculotendinous Adaptations in High and Low- Performance Triathletes · unknown
NCT06266845 — Efficacy of Gamification With Escape-Room for Arrhythmia Identification in Critical Patients · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04961255 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Brasilia
Last refreshed: 5 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04961255.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing