NCT04960774 is a clinical trial of Observational study, no intervention in Severe Periodontitis, sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

Who is sponsoring NCT04960774?

NCT04960774 is sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

What drugs are being tested in NCT04960774?

Interventions in NCT04960774: Observational study, no intervention.

What condition does NCT04960774 study?

NCT04960774 studies Severe Periodontitis, Risk Factors, Gene Polymorphism.

Is NCT04960774 still recruiting?

NCT04960774 is currently status unknown. Last updated 14 July 2021.

Last reviewed 2021-07-14 · How we verify

NCT04960774

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Risk Factors for Severe Periodontitis in 30 to 40 Year Olds: a Retrospective Study

Status unknown Last updated 14 July 2021

What this trial tests

trial testing Observational study, no intervention in Severe Periodontitis in 400 participants. Status unknown.

Timeline

1 April 2021

Primary endpoint
31 December 2022

31 March 2023

Quick facts

Lead sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	400
Start date	1 April 2021
Primary completion	31 December 2022
Estimated completion	31 March 2023
Sites	1 location across China

Drugs / interventions tested

Observational study, no intervention

Conditions studied

Severe Periodontitis — all drugs for Severe Periodontitis →
Risk Factors — all drugs for Risk Factors →
Gene Polymorphism — all drugs for Gene Polymorphism →

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Who can join

Adults 30 to 40, any sex, with Severe Periodontitis or Risk Factors. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Periodontitis is one of the most common oral diseases, which is characterized by alveolar bone resorption and destruction. In China, as a major country in the incidence of periodontitis, there is a huge population of patients with severe periodontitis, and the incidence rate is as high as 12.1-16.1% . Previous studies have suggested that the prevalence and severity of periodontal disease increase with age. However, recent articles on meta analysis and related epidemiological investigations suggest that the prevalence of severe periodontitis does not increase with age, and the prevalence of SP remains at about 10% even in the elderly. In order to comprehensively analyze the risk factors of this population, it is inseparable from the analysis of gene polymorphism. At present, it is considered that the main genes that may be related to the severity of periodontitis are IL-1 α-889, rhIL-talk 1 β + 3953, 6-174, 10-597, CD14-260, CD14-159, MMP1-1607 and so on, which may be related to the severity of periodontitis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04960774 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Second Affiliated Hospital, School of Medicine, Zhejiang University
Last refreshed: 14 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04960774.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing