NCT04959591 is a Phase 3 clinical trial of intravenous acetaminophen in Scoliosis; Adolescence, sponsored by Asan Medical Center.

Who is sponsoring NCT04959591?

NCT04959591 is sponsored by Asan Medical Center.

What drugs are being tested in NCT04959591?

Interventions in NCT04959591: intravenous acetaminophen, intravenous acetaminophen, Placebo.

What condition does NCT04959591 study?

NCT04959591 studies Scoliosis; Adolescence.

Is NCT04959591 still recruiting?

NCT04959591 is currently completed. Last updated 28 December 2022.

Last reviewed 2022-12-28 · How we verify

NCT04959591

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Use of Intravenous Acetaminophen in Pediatrics Undergoing Spinal Fusion Surgery

Completed Phase 3 Last updated 28 December 2022

What this trial tests

Phase 3 trial testing intravenous acetaminophen in Scoliosis; Adolescence in 99 participants. Completed in 22 April 2022.

Timeline

1 June 2021

Primary endpoint
15 April 2022

22 April 2022

Quick facts

Lead sponsor	Asan Medical Center
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	99
Start date	1 June 2021
Primary completion	15 April 2022
Estimated completion	22 April 2022
Sites	1 location across South Korea

Drugs / interventions tested

intravenous acetaminophen — full drug profile →
intravenous acetaminophen — full drug profile →
Placebo

Conditions studied

Scoliosis; Adolescence — all drugs for Scoliosis; Adolescence →

Sponsor

Asan Medical Center

Who can join

Adults 11 to 20, any sex, with Scoliosis; Adolescence. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to investigate whether perioperative intravenous acetaminophen administration reduces postoperative pain and opioid consumption in adolescents and pediatric patients undergoing spinal fusion surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparison of preemptive and preventive intravenous acetaminophen on opioid consumption in pediatrics undergoing posterior spinal fusion surgery: a randomized controlled trial.
Kim YJ, Kim HJ, Kim S, Kim H, et al · · 2024 · cited 1× · PMID 38383005 · DOI 10.4097/kja.23747

Verify or expand the search:

Other recruiting trials for Scoliosis; Adolescence

Currently open trials in the same condition.

NCT06242821 — Yoga for Back Pain in Adolescent Scoliosis · NA · recruiting
NCT06884150 — fNIRS-based Analysis and Evaluation of the Effect of Schroth Rehabilitation on Motor Functions in Adolescent Idiopathic · NA · active not recruiting
NCT06416579 — Comparison of the Efficiency of Schroth Method and Virtual Reality Exercises in Individuals With AIS · NA · recruiting
NCT06093477 — Studying Melatonin and Recovery in Teens · NA · recruiting
NCT05819034 — Conservative Management for Adolescent Idiopathic Scoliosis · NA · recruiting

Other Asan Medical Center trials

Trials by the same sponsor.

NCT07530393 — Blood Viscosity and Outcomes After Elective Craniotomy · not yet recruiting
NCT07010497 — A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Be · Phase 2 · recruiting
NCT07382505 — Prospective Cohort Study of Minimal Residual Disease(MRD) Testing for Early Recurrence Detection in Endometrial and Cerv · not yet recruiting
NCT07489092 — Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge · NA · recruiting
NCT07431762 — Comparison of Anti-Thrombotic Treatments Between Aspirin and Warfarin During Initial Six Months After Bioprpsthetic Hear · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04959591 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Asan Medical Center
Last refreshed: 28 December 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04959591.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing