NCT04958148 is a EARLY_PHASE1 clinical trial of Salt pills in High Blood Pressure, sponsored by Augusta University.

Who is sponsoring NCT04958148?

NCT04958148 is sponsored by Augusta University.

What drugs are being tested in NCT04958148?

Interventions in NCT04958148: Salt pills, Placebo pills.

What condition does NCT04958148 study?

NCT04958148 studies High Blood Pressure.

Is NCT04958148 still recruiting?

NCT04958148 is currently status unknown. Last updated 12 July 2021.

Last reviewed 2021-07-12 · How we verify

NCT04958148

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Salt and Gut Study

Status unknown EARLY_PHASE1 Last updated 12 July 2021

What this trial tests

EARLY_PHASE1 trial testing Salt pills in High Blood Pressure in 40 participants. Status unknown.

Timeline

18 December 2020

Primary endpoint
31 December 2022

31 December 2022

Quick facts

Lead sponsor	Augusta University
Phase	EARLY_PHASE1
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	40
Start date	18 December 2020
Primary completion	31 December 2022
Estimated completion	31 December 2022
Sites	1 location across United States

Drugs / interventions tested

Salt pills
Placebo pills — full drug profile →

Conditions studied

High Blood Pressure — all drugs for High Blood Pressure →

Sponsor

Augusta University

Who can join

Adults 18 to 50, any sex, with High Blood Pressure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

High sodium intake is a significant risk factor for hypertension. Recently, animal studies connect high sodium intake to the gut-immune axis and highlight the gut microbiome as a potential therapeutic target to counteract salt-sensitive conditions and hypertension. The objective of this project is to determine the effects of high salt intake on gut microbiota composition and gut intestine barrier integrity, leading to increased BP in humans. The investigators also hypothesize that high salt intake affects the gut microbiome in a sex-specific manner. In this pilot study, The investigators also test whether telehealth or in-person nutritional coaching help to decrease dietary sodium intake and improve diet quality

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for High Blood Pressure

Currently open trials in the same condition.

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Other Augusta University trials

Trials by the same sponsor.

NCT07341841 — Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study · NA · enrolling by invitation
NCT07489144 — CO-creating Novel, Feasible, and Inclusive Research Methods · NA · active not recruiting
NCT06514014 — Transition From Donor Milk: a Feasibility Study · NA · recruiting
NCT06907992 — A Study Comparing Short-course Antifungal Therapy (SCAT) 7 Day vs Standard 14 Day Antifungal Therapy for Uncomplicated C · not yet recruiting
NCT06058169 — Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04958148 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Augusta University
Last refreshed: 12 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04958148.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing