NCT04955184 is a clinical trial of non-invasive monitoring in Cardiac Output, Low, sponsored by Biobeat Technologies Ltd..

Who is sponsoring NCT04955184?

NCT04955184 is sponsored by Biobeat Technologies Ltd..

What drugs are being tested in NCT04955184?

Interventions in NCT04955184: non-invasive monitoring.

What condition does NCT04955184 study?

NCT04955184 studies Cardiac Output, Low, Cardiac Output, High, Congestive Heart Failure.

Is NCT04955184 still recruiting?

NCT04955184 is currently completed. Last updated 20 July 2022.

Last reviewed 2022-07-20 · How we verify

NCT04955184

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparing Cardiac Output Measurements Using a Wearable, Wireless, Non-invasive PPG-Based Device to a Swan Ganz Catheter

Completed Last updated 20 July 2022

What this trial tests

trial testing non-invasive monitoring in Cardiac Output, Low in 100 participants. Completed in 25 June 2022.

Timeline

10 October 2021

Primary endpoint
15 June 2022

25 June 2022

Quick facts

Lead sponsor	Biobeat Technologies Ltd.
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	10 October 2021
Primary completion	15 June 2022
Estimated completion	25 June 2022
Sites	1 location across Israel

Drugs / interventions tested

non-invasive monitoring

Conditions studied

Cardiac Output, Low — all drugs for Cardiac Output, Low →
Cardiac Output, High — all drugs for Cardiac Output, High →
Congestive Heart Failure — all drugs for Congestive Heart Failure →

Sponsor

Biobeat Technologies Ltd.

Who can join

Adults 18 to 120, any sex, with Cardiac Output, Low or Cardiac Output, High. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Invasive pulmonary capillary wedge pressure measurements using a Swan-Ganz catheter (SGC) is considered the gold standard for cardiac output (CO) monitoring. In this prospective study, we will compare CO measurements between a PPG-based wearable monitor and a SGC in ambulatory CHF patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Pulmonary Artery Catheter Monitoring in Patients with Cardiogenic Shock: Time for a Reappraisal?
Bertaina M, Galluzzo A, Morici N, Sacco A, et al · · 2022 · cited 17× · PMID 35541286 · DOI 10.15420/cfr.2021.32
Assessing Cardiac Flow Measurements Using a Noninvasive Photoplethysmography-Based Device Compared to Invasive Pulmonary Artery Catheter.
Nachman D, Eisenkraft A, Rahamim E, Ibrahimli M, et al · · 2025 · cited 1× · PMID 40845743 · DOI 10.1016/j.jacadv.2025.102093

Verify or expand the search:

Other trials of non-invasive monitoring

Trials testing the same drug.

NCT04220359 — Early Identification of Clinical Deterioration Using a Wearable Monitoring Device · completed
NCT04215627 — Comparing the PiCCO Monitor to the Non-invasive Biobeat (BB)-316PW in ICU Patients · completed

Other recruiting trials for Cardiac Output, Low

Currently open trials in the same condition.

NCT06418022 — Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning · NA · recruiting
NCT04064177 — Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study · recruiting

Other Biobeat Technologies Ltd. trials

Trials by the same sponsor.

NCT07240831 — Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring ( · NA · not yet recruiting
NCT04680039 — Early Warning of Intradialytic Hypotension in Hemodialysis Patients · completed
NCT04635371 — Monitoring Patients With Acute Cardiac Disease Using a Wireless, Wearable, Non-invasive Monitor · completed
NCT04548024 — Relation of Non-invasively Measured Parameters to Clinical Outcomes in CHF Patients · completed
NCT04220359 — Early Identification of Clinical Deterioration Using a Wearable Monitoring Device · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04955184 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Biobeat Technologies Ltd.
Last refreshed: 20 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04955184.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing