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NCT04951128
The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery
Phase 4 trial testing Tranexamic acid injection in Edema in 50 participants. Status unknown.
31 December 2021
Quick facts
| Lead sponsor | Consultants in Ophthalmic and Facial Plastics Surgery |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 August 2021 |
| Primary completion | 31 December 2021 |
| Estimated completion | 1 July 2022 |
| Sites | 4 locations across United States |
Drugs / interventions tested
- Tranexamic acid injection — full drug profile →
- Local anesthetic control — full drug profile →
Conditions studied
- Edema — all drugs for Edema →
- Ecchymosis; Eyelid — all drugs for Ecchymosis; Eyelid →
Sponsor
Consultants in Ophthalmic and Facial Plastics Surgery
Who can join
18 and older, any sex, with Edema or Ecchymosis; Eyelid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Tranexamic acid (TXA) is a synthetic inhibitor of plasminogen lysine receptor that has used to reduce intra-operative bleeding in a number of clinical scenarios. Anecdotally, TXA has used by plastic surgeons to reduce post-operative bruising. To date, there is limited data to valid the benefits and to evaluate the side effects of TXA. The objective of this study is to evaluate the effect of local TXA on edema and ecchymosis in eyelid surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04951128
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Edema
Currently open trials in the same condition.
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- NCT06697470 — Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients · recruiting
- NCT06414759 — Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overlo · Phase 4 · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04951128 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Consultants in Ophthalmic and Facial Plastics Surgery
- Last refreshed: 6 July 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04951128.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing