Who is sponsoring NCT04950296?

NCT04950296 is sponsored by Vedic Lifesciences Pvt. Ltd..

What drugs are being tested in NCT04950296?

Interventions in NCT04950296: Group I: L. plantarum UALp-05TM,, Group II: L. plantarum UALp-05TM,, Microcrystalline cellulose.

What condition does NCT04950296 study?

NCT04950296 studies Irritable Bowel Syndrome With Diarrhea.

Is NCT04950296 still recruiting?

NCT04950296 is currently completed. Last updated 11 July 2022.

Last reviewed 2022-07-11 · How we verify

NCT04950296

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome

Completed NA Last updated 11 July 2022

What this trial tests

NA trial testing Group I: L. plantarum UALp-05TM, in Irritable Bowel Syndrome With Diarrhea in 314 participants. Completed in 5 May 2022.

Timeline

16 September 2021

Primary endpoint
5 May 2022

5 May 2022

Quick facts

Lead sponsor	Vedic Lifesciences Pvt. Ltd.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	314
Start date	16 September 2021
Primary completion	5 May 2022
Estimated completion	5 May 2022
Sites	12 locations across India

Drugs / interventions tested

Group I: L. plantarum UALp-05TM,
Group II: L. plantarum UALp-05TM,
Microcrystalline cellulose — full drug profile →

Conditions studied

Irritable Bowel Syndrome With Diarrhea — all drugs for Irritable Bowel Syndrome With Diarrhea →

Sponsor

Vedic Lifesciences Pvt. Ltd. — full company profile →

Who can join

Adults 18 to 70, any sex, with Irritable Bowel Syndrome With Diarrhea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Several probiotic strains have shown beneficial outcomes in IBS patients, particularly among the Lactobacillus and Bifidobacterium genera, Lactobacillus plantarum (recently reclassified as Lactiplantibacillus plantarum) is a frequently isolated species of the healthy human GI tract that has been studied in numerous GI clinical studies, including for IBS.In the present study, the efficacy and tolerability of L. plantarum (UALp-05TM), will be evaluated in individuals with IBS-D.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Gut Microbiome-Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders.
Sasso JM, Ammar RM, Tenchov R, Lemmel S, et al · · 2023 · cited 100× · PMID 37156006 · DOI 10.1021/acschemneuro.3c00127
Efficacy and dose response of <i>Lactiplantibacillus plantarum</i> in diarrhea-predominant irritable bowel syndrome.
Martoni CJ, Srivastava S, Damholt A, Leyer GJ. · · 2023 · cited 11× · PMID 37576702 · DOI 10.3748/wjg.v29.i28.4451

Verify or expand the search:

Other Vedic Lifesciences Pvt. Ltd. trials

Trials by the same sponsor.

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NCT06859346 — A Clinical Study to Assess the Effect of Tisina Complex on Cognitive Health in Individuals With Mild Cognitive Impairmen · NA · completed
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04950296 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vedic Lifesciences Pvt. Ltd.
Last refreshed: 11 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04950296.

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