Who is sponsoring NCT04949607?

NCT04949607 is sponsored by Centre for Neuro Skills.

What drugs are being tested in NCT04949607?

Interventions in NCT04949607: Inulin fructooligosaccharide.

What condition does NCT04949607 study?

NCT04949607 studies Brain Injury, Chronic, Brain Injuries, Traumatic.

Is NCT04949607 still recruiting?

NCT04949607 is currently completed. Last updated 20 July 2022.

Last reviewed 2022-07-20 · How we verify

NCT04949607

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Traumatic Brain Injury and the Gut Microbiome

Completed NA Last updated 20 July 2022

What this trial tests

NA trial testing Inulin fructooligosaccharide in Brain Injury, Chronic in 23 participants. Completed in 8 June 2022.

Timeline

28 July 2021

Primary endpoint
8 June 2022

8 June 2022

Quick facts

Lead sponsor	Centre for Neuro Skills
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	23
Start date	28 July 2021
Primary completion	8 June 2022
Estimated completion	8 June 2022
Sites	1 location across United States

Drugs / interventions tested

Inulin fructooligosaccharide

Conditions studied

Brain Injury, Chronic — all drugs for Brain Injury, Chronic →
Brain Injuries, Traumatic — all drugs for Brain Injuries, Traumatic →

Sponsor

Centre for Neuro Skills

Who can join

Adults 18 to 70, any sex, with Brain Injury, Chronic or Brain Injuries, Traumatic. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the study is to determine whether administration of a prebiotic, inulin, can improve the symptom complex associated with traumatic brain injury and whether inulin administration can alter the bacteria that live in the gut.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The altered TBI fecal microbiome is stable and functionally distinct.
Pyles RB, Miller AL, Urban RJ, Sheffield-Moore M, et al · · 2024 · cited 11× · PMID 38544523 · DOI 10.3389/fnmol.2024.1341808

Verify or expand the search:

Other Centre for Neuro Skills trials

Trials by the same sponsor.

NCT05786729 — Aerobic Exercise After Traumatic Brain Injury · Phase 1, PHASE2 · enrolling by invitation
NCT03399929 — Traumatic Brain Injury and Stroke Long Term Outcome · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04949607 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre for Neuro Skills
Last refreshed: 20 July 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04949607.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing