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NCT04949464
Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study
NA trial testing Computed Tomography in HIV Infection in 100 participants. Currently enrolling.
30 May 2026
Quick facts
| Lead sponsor | AIDS Malignancy Consortium |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 100 |
| Start date | 22 March 2023 |
| Primary completion | 30 May 2026 |
| Estimated completion | 31 March 2027 |
| Sites | 11 locations across United States |
Drugs / interventions tested
- Computed Tomography
- Smoking Cessation Intervention
Conditions studied
- HIV Infection — all drugs for HIV Infection →
- Tobacco-Related Carcinoma — all drugs for Tobacco-Related Carcinoma →
Sponsor
AIDS Malignancy Consortium
Who can join
Adults 45 to 80, any sex, with HIV Infection or Tobacco-Related Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial evaluates the usefulness of using a smartphone-based HIV-specific smoking cessation intervention at the time of lung cancer screening in helping people living with HIV quit smoking. Positively Smoke Free - Mobile may help patients with HIV quit smoking.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
HIV and lung cancer: a single cancer center experience.
Palecki J, Tucker M, Bernstein A, Melby G, et al · · 2025 · PMID 41103944 · DOI 10.3389/fonc.2025.1600709
Verify or expand the search:
- PubMed search for NCT04949464
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other AIDS Malignancy Consortium trials
Trials by the same sponsor.
- NCT04142398 — Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men · withdrawn
- NCT04142385 — Incidence of HIV Infection in Screening Indian Men Who Have Sex With Men · withdrawn
- NCT05077527 — Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma · Phase 1 · recruiting
- NCT04305691 — Trial of Ixazomib for Kaposi Sarcoma · Phase 2 · recruiting
- NCT05510908 — Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04949464 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by AIDS Malignancy Consortium
- Last refreshed: 23 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04949464.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing