Who is sponsoring NCT04948359?

NCT04948359 is sponsored by Ankara City Hospital Bilkent.

What drugs are being tested in NCT04948359?

Interventions in NCT04948359: Group I (The patients intubated with cuffed ETT of ID number 4.5), Group II (The patients intubated with cuffed ETT of ID number 5.0), Group III ( The patients intubated with cuffed ETT of ID number 5.5).

What condition does NCT04948359 study?

NCT04948359 studies Cuff, Airway Edema, Children, Only, Tracheal Intubation Morbidity.

Is NCT04948359 still recruiting?

NCT04948359 is currently completed. Last updated 16 February 2022.

Last reviewed 2022-02-16 · How we verify

NCT04948359

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Determining Optimal Cuff Volume in Pediatric Patients

Completed Last updated 16 February 2022

What this trial tests

trial testing Group I (The patients intubated with cuffed ETT of ID number 4.5) in Cuff in 120 participants. Completed in 1 October 2021.

Timeline

10 July 2021

Primary endpoint
1 October 2021

1 October 2021

Quick facts

Lead sponsor	Ankara City Hospital Bilkent
Status	Completed
Study type	OBSERVATIONAL
Enrollment	120
Start date	10 July 2021
Primary completion	1 October 2021
Estimated completion	1 October 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Group I (The patients intubated with cuffed ETT of ID number 4.5)
Group II (The patients intubated with cuffed ETT of ID number 5.0)
Group III ( The patients intubated with cuffed ETT of ID number 5.5)

Conditions studied

Cuff — all drugs for Cuff →
Airway Edema — all drugs for Airway Edema →
Children, Only — all drugs for Children, Only →
Tracheal Intubation Morbidity — all drugs for Tracheal Intubation Morbidity →

Sponsor

Ankara City Hospital Bilkent

Who can join

Adults 2 to 12, any sex, with Cuff or Airway Edema. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background and Aim: Cuffed endotracheal tubes with appropriate size, good cuff design and cuff pressure monitoring in pediatric patients can be used safely without increasing airway morbidity. Inflating the endotracheal tube cuff with more than normal volume may lead to decreased capillary blood flow and mucosal damage, while inflating the endotracheal tube cuff with less than normal volume may lead to an increase in the risk of inadequate ventilation and pulmonary aspiration. In this study, we aimed to determine an optimal cuff inflation volume to achieve safe cuff pressure (20-25 cm H2O) in cuffed endotracheal tubes with an inner diameter of 4.5, 5.0, 5.5 mm, which are commonly used in pediatric anesthesia clinical practice.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Determining optimal cuff volume for cuffed endotracheal tubes commonly used in pediatric patients: A prospective observational study.
Güneş K, Sever F, Özmert S. · · 2024 · cited 1× · PMID 38309733 · DOI 10.15537/smj.2024.45.2.20230578

Verify or expand the search:

Other recruiting trials for Cuff

Currently open trials in the same condition.

NCT04410393 — Sacrocolpopexy and Lateral Suspension Operations · active not recruiting
NCT04072588 — Sacrospinous Ligament Fixation and Lateral Suspension Operations · active not recruiting

Other Ankara City Hospital Bilkent trials

Trials by the same sponsor.

NCT07496788 — Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotens · not yet recruiting
NCT07536464 — PEEP Strategies and Mechanical Power in Robotic Surgery · NA · not yet recruiting
NCT07534553 — Mechanical Power Ventilation in RALP · NA · not yet recruiting
NCT07501468 — Ventilation Safety in Beach Chair Shoulder Surgery: SafeLM Versus I-gel · NA · not yet recruiting
NCT07502209 — Suprascapular Nerve PRF in Chronic Shoulder Pain · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04948359 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ankara City Hospital Bilkent
Last refreshed: 16 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04948359.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing