Who is sponsoring NCT04942262?

NCT04942262 is sponsored by Chulalongkorn University.

What drugs are being tested in NCT04942262?

Interventions in NCT04942262: denture adhesive (Polident®, GlaxoSmithKline, Ireland).

What condition does NCT04942262 study?

NCT04942262 studies Complete Denture, Complete Edentulism.

Is NCT04942262 still recruiting?

NCT04942262 is currently completed. Last updated 28 June 2021.

Last reviewed 2021-06-28 · How we verify

NCT04942262

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Oral Health-related Quality of Life and Masticatory Function After Using Denture Adhesive and Denture Liner

Completed Phase 3 Last updated 28 June 2021

What this trial tests

Phase 3 trial testing denture adhesive (Polident®, GlaxoSmithKline, Ireland) in Complete Denture in 80 participants. Completed in 30 April 2020.

Timeline

31 January 2019

Primary endpoint
17 January 2020

30 April 2020

Quick facts

Lead sponsor	Chulalongkorn University
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	supportive care
Enrollment	80
Start date	31 January 2019
Primary completion	17 January 2020
Estimated completion	30 April 2020
Sites	1 location across Thailand

Drugs / interventions tested

denture adhesive (Polident®, GlaxoSmithKline, Ireland) — full drug profile →

Conditions studied

Complete Denture — all drugs for Complete Denture →
Complete Edentulism — all drugs for Complete Edentulism →

Sponsor

Chulalongkorn University

Who can join

Adults 40 to 90, any sex, with Complete Denture or Complete Edentulism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

80 complete denture (CD) wearers participated in the quasi-experimental study. Two outcomes were: 1) oral health-related quality of life (OHRQoL) assessed using the Oral Impacts on Daily Performances index, and 2) masticatory performance, determined by a peanut particle size after 20-stroke mastication. Denture retention and stability were evaluated using the Chulalongkorn University (CU)-modified Kapur method to classify the CD into acceptable or unacceptable quality. Data were collected at 3-time points: 1) at baseline (T0), 2) after a 1-month trial of denture adhesive (DA) use (T1), at which time the participants decided whether to continue using DA, and 3) 1-month after continued or discontinued using DA (T2).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Decision to use denture adhesive in complete denture wearers after one-month run-in period: A quasi-experimental study.
Limpuangthip N, Tumrasvin W, Thongyoi B. · · 2022 · PMID 36454894 · DOI 10.1371/journal.pone.0276760

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04942262 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chulalongkorn University
Last refreshed: 28 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04942262.

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