Adults 18 to 99, any sex, with COVID-19 Infection. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
COVID Ordinal Outcome ScalePrimary· Baseline through Day 7 after completion of therapy
Outcome measured clinical status of the participant defined by the COVID Ordinal Outcome Scale on Day 7:
0 = Uninfected, no viral RNA detected
1. = Asymptomatic, viral RNA detected
2. = Symptomatic, independent
3. = Symptomatic, assistance needed
4. = Hospitalized, no oxygen needed
5. = Hospitalized, oxygen by mask or nasal prongs
6. = Hospitalized, oxygen by NIV or high flow
7. = Intubation and mechanical ventilation, pO2/FiO2 ≥150 or SpO2/FiO2 ≥200
8. = Mechanical ventilation, pO2/FiO2 \<150 (SpO2/FiO2 \<200) or vasopressors
9. = Mechanical ventilation, pO2/FiO2 \<150 and vasopressors, dia
Outcome Score = 0
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
0
Placebo
0
Outcome Score = 1
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
0
Placebo
0
Outcome Score = 2
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
1
Placebo
1
Outcome Score = 3
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
2
Placebo
1
Outcome Score = 4
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
0
Placebo
0
Outcome Score = 5
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
1
Placebo
1
Outcome Score = 6
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
2
Placebo
4
Outcome Score = 7
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
0
Placebo
0
Change in Oxygen Requirements From Baseline to Day 7 by Treatment GroupSecondary· baseline and 7 days
Measured by liters of oxygen per minute to maintain saturation above 90%
Group
Value
95% CI
Magnesium Citrate Plus a Probiotic Arm:
2.00
0 – 6
Placebo
9.00
5.00 – 15.00
Sponsor's own description
We are conducting an investigator-initiated, single center, blinded, placebo-controlled, randomized clinical trial evaluating magnesium citrate combined with a probiotic for the treatment of adults hospitalized with COVID-19.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
NCT07013474 — A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
· Phase 3
· recruiting
NCT06965751 — A Study on the Effects in Healthy People of a New Drug Called PDI204 for Treating COVID-19
· Phase 1
· active not recruiting
NCT06923137 — A Study to Learn About How Well Yearly Updates to the COVID-19 Vaccine Work to Protect People From COVID-19 and How Much
· active not recruiting
NCT05672355 — A Vaccine Booster (GEO-CM04S1) for the Prevention of COVID-19 in Patients With Chronic Lymphocytic Leukemia
· Phase 2
· recruiting
NCT05774093 — Evaluation of COVID-19 Immune Barrier and Reinfection Risk
· recruiting
Other Vanderbilt University Medical Center trials
Trials by the same sponsor.
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· not yet recruiting
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· NA
· not yet recruiting
NCT07295288 — Botox Injections in Non-Cranial Nerve VII Innervated Muscles for Facial Synkinesis
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· not yet recruiting
NCT07431541 — Topical Carboxytherapy Paste Following Microneedling
· Phase 1, PHASE2
· not yet recruiting
NCT07224711 — The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery
· Phase 4
· not yet recruiting
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University Medical Center
Last refreshed: 13 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04941703.