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NCT04939545: SPICA
Study of Postoperative ICC Analgesia
Phase 3 trial testing Ropivacain in Postoperative Analgesia in 32 participants. Completed in 20 October 2023.
20 March 2023
Quick facts
| Lead sponsor | University Hospital, Basel, Switzerland |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 32 |
| Start date | 15 December 2021 |
| Primary completion | 20 March 2023 |
| Estimated completion | 20 October 2023 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Ropivacain — full drug profile →
- NaCl 0.9%
Conditions studied
- Postoperative Analgesia — all drugs for Postoperative Analgesia →
Sponsor
University Hospital, Basel, Switzerland
Who can join
18 and older, any sex, with Postoperative Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is to examine the analgesic effectiveness of continuous loco-regional analgesic application (ropivacaine) through surgically placed Intercostal Catheter (ICC) and to establish correctly this method as a possible standard of care in the postoperative analgesia after Video-assisted thoracoscopic surgery (VATS) anatomical lung resection.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The efficacy of loco-regional ropivacaine analgesia via intercostal catheters after lung resection: a randomized, double-blind, placebo-controlled, superiority study.
Hojski A, Krämer M, Gecas P, Djakovic Z, et al · · 2024 · PMID 39352775 · DOI 10.1093/ejcts/ezae342
Verify or expand the search:
- PubMed search for NCT04939545
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Postoperative Analgesia
Currently open trials in the same condition.
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Other University Hospital, Basel, Switzerland trials
Trials by the same sponsor.
- NCT07444788 — Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants · Phase 1 · recruiting
- NCT07494214 — Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants · Phase 1 · recruiting
- NCT07419048 — Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status · recruiting
- NCT06978777 — Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity · NA · recruiting
- NCT07273630 — Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04939545 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Basel, Switzerland
- Last refreshed: 24 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04939545.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing