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NCT04939233

Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries

Completed NA Results posted Last updated 20 October 2025
What this trial tests

NA trial testing Exoskeleton glove in Brachial Plexus Injury in 3 participants. Completed in 28 February 2023.

Timeline
1 July 2021
Primary endpoint
20 May 2022
28 February 2023

Quick facts

Lead sponsorCarilion Clinic
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposedevice feasibility
Enrollment3
Start date1 July 2021
Primary completion20 May 2022
Estimated completion28 February 2023
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Carilion Clinic

Who can join

Adults 18 to 69, any sex, with Brachial Plexus Injury. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Number of Successful Grasp Trials Per Participant Using Robotic Hand Orthosis Primary · The total expected time for the study is about 2 hours.

Southampton Hand Assessment Procedure (SHAP) Construct Measured: Functional hand performance based on prehensile and Activities of Daily Living (ADL) tasks. Structure: 6 Abstract Object Tasks (grip patterns). The five most used grasp types in ADLs were selected for the experiments, which include cylinder grasp, sphere grasp, tip grasp, tripod grasp, and lateral grasp. We selected ten objects that belong to different grasp types for the experiments. Each object was grasped for five times by each participant. Scoring: Successful vs unsuccessful grasps with 10 different objects Interpretation:

GroupValue95% CI
Exoskeleton Glove13.20 – 15

Sponsor's own description

The proposed research, the development of an innovative robotic hand orthosis with intelligent grasping control, is relevant to public health as it will restore a large measure of functionality to the paralyzed hand of a person who has suffered a brachial plexus injury. The proposed orthosis will utilize novel technology that will result in a device that is compact, portable, dexterous, and intuitively controllable while overcoming the disadvantages of previously developed orthoses that rendered them difficult to use. The restoration of functionality to ones hands will significantly improve their quality of life as well as their ability to again participate in the workforce and complete dexterous activities in their daily lives.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other Carilion Clinic trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04939233.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing