NCT04938284 is a NA clinical trial of PAS in Spinal Plasticity, sponsored by Helsinki University Central Hospital.

Who is sponsoring NCT04938284?

NCT04938284 is sponsored by Helsinki University Central Hospital.

What drugs are being tested in NCT04938284?

Interventions in NCT04938284: PAS, VNS.

What condition does NCT04938284 study?

NCT04938284 studies Spinal Plasticity.

Is NCT04938284 still recruiting?

NCT04938284 is currently completed. Last updated 13 May 2025.

Last reviewed 2025-05-13 · How we verify

NCT04938284

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Combining PAS to Non-invasive VNS

Completed NA Last updated 13 May 2025

What this trial tests

NA trial testing PAS in Spinal Plasticity in 10 participants. Completed in 30 December 2021.

Timeline

1 July 2021

Primary endpoint
30 December 2021

30 December 2021

Quick facts

Lead sponsor	Helsinki University Central Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	10
Start date	1 July 2021
Primary completion	30 December 2021
Estimated completion	30 December 2021
Sites	1 location across Finland

Drugs / interventions tested

Conditions studied

Spinal Plasticity — all drugs for Spinal Plasticity →

Sponsor

Helsinki University Central Hospital

Who can join

Adults 18 to 75, any sex, with Spinal Plasticity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Vagus nerve stimulation (VNS) and paired associative stimulation (PAS) have been shown to have efficacy in improving the results of motor rehabilitation after stroke and spinal cord injury, respectively. Here we will investigate in healthy subjects the synergistic effect of these stimulation modalities on motor-evoked potential (MEP) potentiation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of PAS

Trials testing the same drug.

NCT02284087 — Paired Associative Stimulation in Post-stroke Hand Motor Deficits · completed

Other Helsinki University Central Hospital trials

Trials by the same sponsor.

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NCT07458984 — FMT Capsules for rCDI · Phase 3 · not yet recruiting
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NCT07155629 — Neoadjuvant Treatment vs Upfront Surgery for Left-Sided Pancreatic Cancer · Phase 3 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04938284 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Helsinki University Central Hospital
Last refreshed: 13 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04938284.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing