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NCT04931966
Comparision of IPACK and Periarticular Block With Adductor Block Alone After Total Knee Artroplasty
NA trial testing block in Osteo Arthritis Knee in 105 participants. Completed in 17 August 2021.
8 August 2021
Quick facts
| Lead sponsor | Karaman Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 105 |
| Start date | 22 June 2021 |
| Primary completion | 8 August 2021 |
| Estimated completion | 17 August 2021 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- block
- adductor canal block — full drug profile →
- Adductor Canal Block plus IPACK Block — full drug profile →
- adductor Canal Block plus PAI Block
Conditions studied
- Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →
Sponsor
Karaman Training and Research Hospital
Who can join
Adults 18 to 85, any sex, with Osteo Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
105 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of three groups, namely group A (n=35), where an adductor canal block, group B (N:35) where an adductor canal block with IPCAK, and group C (n=35) where an adductor canal block with PAI will be performed preoperatively. All patients will receive a standardized multimodal approach. NRS scores will be evaluated in static and dynamic conditions during the first 48 hours postoperatively.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of iPACK and periarticular block with adductor block alone after total knee arthroplasty: a randomized clinical trial.
Et T, Korkusuz M, Basaran B, Yarımoğlu R, et al · · 2022 · cited 24× · PMID 35157136 · DOI 10.1007/s00540-022-03047-6
Verify or expand the search:
- PubMed search for NCT04931966
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of block
Trials testing the same drug.
- NCT06558123 — Deep Parasternal Intercostal Plane (DPIP) Block · completed
Other recruiting trials for Osteo Arthritis Knee
Currently open trials in the same condition.
- NCT07258693 — Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeu · NA · active not recruiting
- NCT07141316 — Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty · NA · active not recruiting
- NCT06485843 — An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Jo · Phase 2 · recruiting
- NCT06965946 — Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis · NA · recruiting
- NCT06058169 — Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) · NA · recruiting
Other Karaman Training and Research Hospital trials
Trials by the same sponsor.
- NCT07130552 — Comparison of Distal IPACK and Popliteal Plexus Block Combined With Femoral Triangle Block After Total Knee Arthroplasty · NA · recruiting
- NCT07102407 — Effect of a Constructivist Educational Program on Preventing Ventilator-Associated Pneumonia in Intensive Care Units · NA · recruiting
- NCT06616740 — Effects of Paratracheal Compression and Cricoid Compression on LMA ProSeal Placement · NA · completed
- NCT06605937 — The Effect of Postoperative Eustachian Milking Maneuver on Eustachian Tube Dysfunction · completed
- NCT06634680 — Effects of Different Parental Involvement on Anxiety and Delirium · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04931966 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karaman Training and Research Hospital
- Last refreshed: 18 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04931966.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing