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A Study of Sacituzumab With Chemoimmunotherapy to Treat Advanced Triple-Negative Breast Cancer After Prior Therapies
This is a phase 1b/2 open-label study to evaluate the safety and efficacy of sacituzumab govitecan-hziy in combination with chemoimmunotherapy (cyclophosphamide, N-803, and PD-L1 t-haNK) in subjects with Triple Negative Breast Cancer (TNBC) after at least 2 prior treatments for metastatic disease.
Details
| Lead sponsor | ImmunityBio, Inc. |
|---|---|
| Phase | PHASE1, PHASE2 |
| Status | TERMINATED |
| Enrolment | 3 |
| Start date | Wed Sep 08 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Dec 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Advanced Triple Negative Breast Cancer
Interventions
- N-803
- PD-L1 t-haNK
- Sacituzumab Govitecan-Hziy
- Cyclophosphamide
Countries
United States