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NCT04923984: EMMA-Can

Embolization of Middle Meningeal Artery for Subdural Hematoma in Canada (EMMA Can)

Recruiting now NA Last updated 3 February 2026
What this trial tests

NA trial testing Embolization of the middle meningeal artery in Subdural Hematoma in 1,000 participants. Currently enrolling.

Timeline
1 May 2021
Primary endpoint
31 December 2029
31 December 2029

Quick facts

Lead sponsorUniversity of Manitoba
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment1,000
Start date1 May 2021
Primary completion31 December 2029
Estimated completion31 December 2029
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

University of Manitoba

Who can join

18 and older, any sex, with Subdural Hematoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

EMMA-Can is a prospective cohort study to assess the safety and effectiveness of MMA-embolization for the treatment of CSDH. Hypothesis- EMMA reduces the recurrence rate of CSDH with or without concomitant surgical evacuation.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Multidisciplinary consensus-based statement on the current role of middle meningeal artery embolization (MMAE) in chronic SubDural hematoma (cSDH).
    Bartek J, Biondi A, Bonhomme V, Castellan L, et al · · 2024 · cited 13× · PMID 39717364 · DOI 10.1016/j.bas.2024.104143
  2. Newer treatment paradigm improves outcomes in the most common neurosurgical disease of the elderly: a literature review of middle meningeal artery embolization for chronic subdural hematoma.
    Debs LH, Walker SE, Rahimi SY. · · 2024 · cited 13× · PMID 38691299 · DOI 10.1007/s11357-024-01173-5
  3. A systematic review of middle meningeal artery embolization for minimally symptomatic chronic subdural haematomas that do not require immediate evacuation.
    Rojas-Villabona A, Mohamed S, Kennion O, Padmanabhan R, et al · · 2023 · cited 7× · PMID 38021007 · DOI 10.1016/j.bas.2023.102672

Verify or expand the search:

Other recruiting trials for Subdural Hematoma

Currently open trials in the same condition.

Other University of Manitoba trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04923984.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing