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NCT04923750: IRA-PMSI
Detection of Acute Renal Failure Using Hospital Coding Data
trial in Acute Renal Failure in 498 participants. Completed in 31 December 2023.
31 December 2023
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire, Amiens |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 498 |
| Start date | 3 June 2021 |
| Primary completion | 31 December 2023 |
| Estimated completion | 31 December 2023 |
| Sites | 1 location across France |
Conditions studied
- Acute Renal Failure — all drugs for Acute Renal Failure →
- Iatrogenic Effect — all drugs for Iatrogenic Effect →
- Uremic Toxin — all drugs for Uremic Toxin →
Sponsor
Centre Hospitalier Universitaire, Amiens
Who can join
18 and older, any sex, with Acute Renal Failure or Iatrogenic Effect. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
AKI is a rapid and usually reversible impairment of kidney function that is life-threatening in the short term well described by the "Kidney Disease: Improving Global Outcomes - KDIGO" classification of 2012. Whatever etiology of acute renal failure, drug iatrogeny still has its place. Hospital data from the information systems medicalization program (PMSI) can be used for epidemiological research. No study has yet been performed on these data to assess drug-related AKI. However, it should be remembered that these databases were not originally designed for research purposes but for reimbursement of care. Therefore, before conducting a large-scale study, it remains important to determine the validity and representativeness of the codes used for coding the studied events. The objective of this project is therefore to validate the use of hospital coding to identify AKI.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Risk factors for and characteristics of community- and hospital-acquired drug-induced acute kidney injuries.
Rey A, Gras-Champel V, Choukroun G, Masmoudi K, et al · · 2022 · cited 6× · PMID 35037310 · DOI 10.1111/fcp.12758 -
Use of the Capture-Recapture Method to Estimate the Frequency of Community- and Hospital-Acquired Drug-Induced Acute Kidney Injuries in French Databases.
Rey A, Gras V, Moragny J, Choukroun G, et al · · 2022 · cited 4× · PMID 35865950 · DOI 10.3389/fphar.2022.899164
Verify or expand the search:
- PubMed search for NCT04923750
- Europe PMC full search
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Related trials
Other recruiting trials for Acute Renal Failure
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04923750 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire, Amiens
- Last refreshed: 3 July 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04923750.
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