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NCT04923399
Transcriptome Sequencing Analysis of Whole Blood From Patients With Trigeminal Neuralgia
trial in Trigeminal Neuralgia in 20 participants. Status unknown.
1 June 2023
Quick facts
| Lead sponsor | Peking University People's Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 June 2021 |
| Primary completion | 1 June 2023 |
| Estimated completion | 1 June 2023 |
Conditions studied
- Trigeminal Neuralgia — all drugs for Trigeminal Neuralgia →
- Blood — all drugs for Blood →
- Plasma — all drugs for Plasma →
- Cerebrospinal Fluid — all drugs for Cerebrospinal Fluid →
Sponsor
Peking University People's Hospital
Who can join
Adults 20 to 75, any sex, with Trigeminal Neuralgia or Blood. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Trigeminal neuralgia is a type of neuropathic pain that brings great physical and psychological pressure to patients. Chronic pain can cause changes in the composition of central and peripheral body fluids, and these changes may be useful for the prediction and treatment of pain. In this study, the whole blood of patients with trigeminal neuralgia and non-chronic pain was collected, and transcriptome sequencing (RNA-seq) was performed to determine the peripheral transcriptome changes of trigeminal neuralgia (TN) patients. And compare the expression of neuropeptide Y (NPY) in plasma and cerebrospinal fluid of TN and non-chronic pain patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Whole Blood Transcriptome Analysis in Patients with Trigeminal Neuralgia: a Prospective Clinical Study.
Liu T, Xu C, Guo J, He Z, et al · · 2024 · cited 1× · PMID 38300339 · DOI 10.1007/s12031-024-02195-6
Verify or expand the search:
- PubMed search for NCT04923399
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Trigeminal Neuralgia
Currently open trials in the same condition.
- NCT07252453 — Comparison b/w Carbamazepine vs Oxcarbazepine in Treatment of Trigeminal Neuralgia · NA · active not recruiting
- NCT06684275 — Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia · NA · recruiting
- NCT06620172 — CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia · NA · recruiting
- NCT06849219 — Comparison of Oxcarbazepine Versus Carbamazepine in the Management of Trigeminal Neuralgia · Phase 4 · active not recruiting
- NCT06216886 — OnabotulinumtoxinA for Trigeminal Neuralgia · Phase 4 · recruiting
Other Peking University People's Hospital trials
Trials by the same sponsor.
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- NCT07500441 — Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04923399 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking University People's Hospital
- Last refreshed: 11 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04923399.
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