Who is sponsoring NCT04922619?

NCT04922619 is sponsored by MED-EL Elektromedizinische Geräte GesmbH.

What drugs are being tested in NCT04922619?

Interventions in NCT04922619: tonotopy based fitting then default fitting, default fitting then tonotopy based fitting.

What condition does NCT04922619 study?

NCT04922619 studies Sensorineural Hearing Loss, Bilateral.

Is NCT04922619 still recruiting?

NCT04922619 is currently completed. Last updated 20 October 2021.

Last reviewed 2021-10-20 · How we verify

NCT04922619

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Study of Music and Speech Perception in New Cochlear Implanted Subjects Using or Not a Tonotopy Based Fitting

Completed NA Last updated 20 October 2021

What this trial tests

NA trial testing tonotopy based fitting then default fitting in Sensorineural Hearing Loss, Bilateral in 26 participants. Completed in 30 September 2021.

Timeline

10 June 2021

Primary endpoint
31 August 2021

30 September 2021

Quick facts

Lead sponsor	MED-EL Elektromedizinische Geräte GesmbH
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	other
Enrollment	26
Start date	10 June 2021
Primary completion	31 August 2021
Estimated completion	30 September 2021
Sites	1 location across France

Drugs / interventions tested

tonotopy based fitting then default fitting
default fitting then tonotopy based fitting

Conditions studied

Sensorineural Hearing Loss, Bilateral — all drugs for Sensorineural Hearing Loss, Bilateral →

Sponsor

MED-EL Elektromedizinische Geräte GesmbH — full company profile →

Who can join

18 and older, any sex, with Sensorineural Hearing Loss, Bilateral. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Main objective: Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the perception speech in noise. Secondary objectives: Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the perception of musical elements (contour test). Show the non inferiority of tonotopy based fitting strategy compared to default fitting strategy on the perception of speech elements in quiet. Show the superiority of tonotopy based fitting strategy compared to default fitting strategy on the qualitative preference for the listening of musical pieces.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Tonotopic and Default Frequency Fitting for Music Perception in Cochlear Implant Recipients: A Randomized Clinical Trial.
Creff G, Bernard-Le Liboux N, Coudert P, Bourdon H, et al · · 2024 · cited 6× · PMID 39264640 · DOI 10.1001/jamaoto.2024.2895

Verify or expand the search:

Other recruiting trials for Sensorineural Hearing Loss, Bilateral

Currently open trials in the same condition.

NCT06737185 — Comparison of Speech Understanding Between Tonotopy-based Fitting and Setting Based on Evolutionary Algorithms · NA · recruiting
NCT06723262 — Speech Perception of a Tonotopy-based Fitting for Cochlear Implant Recipients for 6 Months With Conventional Setting · NA · recruiting
NCT05955469 — Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting · NA · recruiting
NCT05898659 — Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting With or Without Synchronization · NA · recruiting
NCT05402813 — Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes · recruiting

Other MED-EL Elektromedizinische Geräte GesmbH trials

Trials by the same sponsor.

NCT07213505 — This Clinical Investigation Assesses the Safety and Performance of a New Beamformer for MED-EL Cochlear Implant Recipien · NA · recruiting
NCT06817928 — Investigating the Performance and Safety of the AudioKey 3, a Device That Provides Remote Control Options and Status Inf · completed
NCT06737185 — Comparison of Speech Understanding Between Tonotopy-based Fitting and Setting Based on Evolutionary Algorithms · NA · recruiting
NCT06723262 — Speech Perception of a Tonotopy-based Fitting for Cochlear Implant Recipients for 6 Months With Conventional Setting · NA · recruiting
NCT05955469 — Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04922619 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by MED-EL Elektromedizinische Geräte GesmbH
Last refreshed: 20 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04922619.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing