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NCT04921722
Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies
Phase 4 trial testing Percutaneous sirolimus in Kaposiform Hemangioendothelioma in 75 participants. Status unknown.
1 November 2025
Quick facts
| Lead sponsor | Children's Hospital of Fudan University |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 22 October 2021 |
| Primary completion | 1 November 2025 |
| Estimated completion | 1 November 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Percutaneous sirolimus — full drug profile →
- Oral sirolimus
Conditions studied
- Kaposiform Hemangioendothelioma — all drugs for Kaposiform Hemangioendothelioma →
- Tufted Angioma — all drugs for Tufted Angioma →
- Superficial Vascular Anomalies — all drugs for Superficial Vascular Anomalies →
- Superficial Lymphatic Malformations — all drugs for Superficial Lymphatic Malformations →
Sponsor
Children's Hospital of Fudan University
Who can join
Adults 0 to 18, any sex, with Kaposiform Hemangioendothelioma or Tufted Angioma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, we investigate the safety and efficacy of topical sirolimus in the treatment of superficial complicated vascular anomolies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04921722
- Europe PMC full search
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- ESMO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04921722 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Children's Hospital of Fudan University
- Last refreshed: 15 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04921722.
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