Last reviewed · How we verify
NCT04919720: RESPOND
Rescue for Emergency Surgery Patients Observed to uNdergo Acute Deterioration
NA trial testing FRAM Model and Human Factors/Quality Improvement Intervention in Failure to Rescue in 9,064 participants. Status unknown.
28 February 2026
Quick facts
| Lead sponsor | University of Oxford |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 9,064 |
| Start date | 5 March 2021 |
| Primary completion | 28 February 2026 |
| Estimated completion | 28 February 2026 |
| Sites | 2 locations across United Kingdom |
Drugs / interventions tested
- FRAM Model and Human Factors/Quality Improvement Intervention
Conditions studied
- Failure to Rescue — all drugs for Failure to Rescue →
- Emergencies — all drugs for Emergencies →
Sponsor
University of Oxford
Who can join
Adults 18 to 100, any sex, with Failure to Rescue or Emergencies. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a Five Year programme designed to identify and evaluate human factors interventions to improve the response to patients deteriorating following emergency surgery. The programme comprises four work packages: Work Package 1: Qualitative interviews and observations to analyse current rescue systems; Work Package 2: Identify and co-design interventions to improve rescue systems,involving both staff and patients and carers; Work Package 3: Mixed-methods feasibility trial across 3 sites in England, Work Package 4: Step-wedge randomised control trial based across 24 hospital sites in England, evaluating efficacy of interventions in improving response to deteriorating patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04919720
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Failure to Rescue
Currently open trials in the same condition.
- NCT06997328 — '5 Rs to Rescue' A Cluster Trial With an Embedded Process Evaluation · recruiting
Other University of Oxford trials
Trials by the same sponsor.
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- NCT07345910 — Environment, Pathogens, and Host Interactions in Melioidosis · not yet recruiting
- NCT07434973 — Stratification and Treatment in Early Psychosis Study - PROMOTE · Phase 3 · not yet recruiting
- NCT07460401 — 'Do Patient Characteristics Associate With Poor Outcome With Femoral Acetabular Impingement Syndrome (FAIS) Following Ph · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04919720 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oxford
- Last refreshed: 9 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04919720.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing