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NCT04915898: HAPPIER-1
Hospital-acquired Pneumonia Prevention: Intervention, Evaluation & Research
NA trial testing Oral Hygiene - teeth brushing in Healthcare-Associated Pneumonia in 8,709 participants. Completed in 30 April 2020.
30 November 2019
Quick facts
| Lead sponsor | Orlando Health, Inc. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 8,709 |
| Start date | 1 October 2018 |
| Primary completion | 30 November 2019 |
| Estimated completion | 30 April 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Oral Hygiene - teeth brushing
Conditions studied
- Healthcare-Associated Pneumonia — all drugs for Healthcare-Associated Pneumonia →
Sponsor
Orlando Health, Inc. — full company profile →
Who can join
18 and older, any sex, with Healthcare-Associated Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine the effectiveness of a universal, standardized oral care protocol on prevention of non-ventilated hospital-acquired pneumonia (NV-HAP) in the acute care setting. In the course of the year-long study, the research team will provide educational and materials support for oral hygiene on two interventional units (one medical; one surgical) and two control units (one matched medical; one surgical). At the end of the study, the research team will evaluate existing hospital data to determine the number of NV-HAPs in the interventional and control groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04915898
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Orlando Health, Inc. trials
Trials by the same sponsor.
- NCT07406698 — Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis · NA · recruiting
- NCT06178315 — EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis · NA · recruiting
- NCT06576869 — Timing of Tourniquet Release · NA · completed
- NCT04231279 — Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency · Phase 3 · terminated
- NCT05043415 — Randomized Trial of Immediate Endoscopic Necrosectomy vs. Step-up Endoscopic Interventions in Necrotizing Pancreatitis · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04915898 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Orlando Health, Inc.
- Last refreshed: 12 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04915898.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing