NCT04914884 is a clinical trial of intraocular fluid detection in Intraocular Inflammation, sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

Who is sponsoring NCT04914884?

NCT04914884 is sponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University.

What drugs are being tested in NCT04914884?

Interventions in NCT04914884: intraocular fluid detection.

What condition does NCT04914884 study?

NCT04914884 studies Intraocular Inflammation.

Is NCT04914884 still recruiting?

NCT04914884 is currently status unknown. Last updated 7 June 2021.

Last reviewed 2021-06-07 · How we verify

NCT04914884

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intraocular Fluid Detection in Endophthalmitis

Status unknown Last updated 7 June 2021

What this trial tests

trial testing intraocular fluid detection in Intraocular Inflammation in 100 participants. Status unknown.

Timeline

1 June 2021

Primary endpoint
1 October 2021

1 January 2022

Quick facts

Lead sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 June 2021
Primary completion	1 October 2021
Estimated completion	1 January 2022
Sites	1 location across China

Drugs / interventions tested

intraocular fluid detection

Conditions studied

Intraocular Inflammation — all drugs for Intraocular Inflammation →

Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Who can join

Adults 20 to 80, any sex, with Intraocular Inflammation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Endophthalmitis is also called vitreous inflammation. Broadly speaking, it refers to all kinds of serious intraocular inflammation, such as vitreitis, anterior chamber empyema and eye pain caused by intraocular infection, intraocular foreign body, tumor necrosis, severe non infectious uveitis, lens cortex allergy, etc. Clinically, it generally refers to infectious endophthalmitis caused by bacteria, fungi or parasites. According to the different ways of infection, it can be divided into exogenous endophthalmitis and endogenous endophthalmitis. Exogenous endophthalmitis is more common. When inflammation involves sclera or extraocular orbital tissue, it is called "panophthalmia". Endophthalmitis is a kind of serious intraocular inflammation which can lead to the loss of visual function. Early diagnosis and treatment is the key. Studies have found that the changes of cytokines in aqueous humor are helpful for the diagnosis of endophthalmitis. Okhrvai et al. Also pointed out that the application of PCR can reduce the diagnosis time of endophthalmitis. This study mainly verified the use of molecular biology technology to detect the changes of VCAM, ICAM-1 and other cytokines, bacteria, viruses, fungi, Toxoplasma gondii IgG in patients' intraocular fluid, including aqueous humor and vitreous humor, so as to timely judge the etiology and progress of endophthalmitis, and provide reference for diagnosis and treatment.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04914884 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Second Affiliated Hospital, School of Medicine, Zhejiang University
Last refreshed: 7 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04914884.

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