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NCT04909398: PupDyn
Pupil Dynamics and Color Vision for the Detection of Eye Diseases
NA trial testing Dynamic pupillometry sessions in Retinitis Pigmentosa in 60 participants. Completed in 22 May 2019.
22 March 2018
Quick facts
| Lead sponsor | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 60 |
| Start date | 22 March 2018 |
| Primary completion | 22 March 2018 |
| Estimated completion | 22 May 2019 |
| Sites | 1 location across France |
Drugs / interventions tested
- Dynamic pupillometry sessions
Conditions studied
- Retinitis Pigmentosa — all drugs for Retinitis Pigmentosa →
- Leber's Hereditary Optic Neuropathy — all drugs for Leber's Hereditary Optic Neuropathy →
- Stargardt Disease — all drugs for Stargardt Disease →
Sponsor
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Who can join
Adults 18 to 60, any sex, with Retinitis Pigmentosa or Leber's Hereditary Optic Neuropathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The development of new oculometry techniques allows fine and dynamic measurements of pupillary diameter and use in routine clinical practice. The preliminary results obtained with innovative devices on healthy sjuets make it possible to envisage a clinical study on a population of patients suffering from retinal pathologies. This is a "proof of concept" study, which, if the expected results are confirmed, will make it possible to consider a study on a larger population, as well as the industrial development of a commercial device.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Uncovering the Characteristics of Pupil Cycle Time (PCT) in Neuropathies and Retinopathies.
Trinquet L, Ajasse S, Chavane F, Legras R, et al · · 2025 · PMID 40700079 · DOI 10.3390/vision9030051
Verify or expand the search:
- PubMed search for NCT04909398
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Retinitis Pigmentosa
Currently open trials in the same condition.
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- NCT07228793 — Natural History Study of Patients With EYS-Associated RP · recruiting
- NCT06319872 — The Effects of Disulfiram (Antabuse®) on Visual Acuity in Patients With Retinal Degeneration · Phase 1 · recruiting
- NCT06936787 — An Open-label, Dose-ascending Study of IGT001 for Retinitis Pigmentosa · Phase 1 · recruiting
Other Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts trials
Trials by the same sponsor.
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- NCT05747781 — STReetlab Assessment Tool of Activities Daily Living in Glaucoma Patient · NA · not yet recruiting
- NCT04239196 — Efficacy of Tocilizumab for the Treatment of Acute AION Related to GCA · Phase 2 · unknown
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04909398 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
- Last refreshed: 1 June 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04909398.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing