NCT04906850 (VARICOVID) is a clinical trial in Covid19, sponsored by Centre Hospitalier Régional Metz-Thionville.

Who is sponsoring NCT04906850?

NCT04906850 is sponsored by Centre Hospitalier Régional Metz-Thionville.

Is NCT04906850 still recruiting?

NCT04906850 is currently completed. Last updated 2 June 2021.

Last reviewed 2021-06-02 · How we verify

NCT04906850: VARICOVID

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the New Variant 501Y.V2 of COVID-19

Completed Last updated 2 June 2021

What this trial tests

trial in Covid19 in 250 participants. Completed in 15 May 2021.

Timeline

1 March 2021

Primary endpoint
15 April 2021

15 May 2021

Quick facts

Lead sponsor	Centre Hospitalier Régional Metz-Thionville
Status	Completed
Study type	OBSERVATIONAL
Enrollment	250
Start date	1 March 2021
Primary completion	15 April 2021
Estimated completion	15 May 2021
Sites	2 locations across France

Conditions studied

Covid19 — all drugs for Covid19 →

Sponsor

Centre Hospitalier Régional Metz-Thionville

Who can join

18 and older, any sex, with Covid19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In January 2021, the incidence of COVID-19-and its mortality started rising for the third time in France. This rise may associate with three emerging variants, namely, V1, V2, and V3, which are the 20I/501Y.V1 ("English"), 20H/501Y.V2 ("South African"), and 20J/501Y.V3 ("Brazilian") variants, respectively. V1 was recently suggested to increase mortality in people in the United Kingdom who tested positive for COVID-19 on community screening. Very little is known about V2 infection, including its outcomes relative to other strains. In early 2021, V2 spread to the Grand-Est region (northeastern France). Here, the investigators aimed to report mortality data of patients admitted in ICU between February and April 2021 in 3 hospitals in Grand-Est: Metz, Thionville and Nancy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparison of SARS-CoV-2 Variants of Concern Alpha (B.1.1.7) vs. Beta (B.1.351) in Critically Ill Patients: A Multicenter Cohort Study.
Louis G, Belveyre T, Goetz C, Gibot S, et al · · 2022 · cited 6× · PMID 35360736 · DOI 10.3389/fmed.2022.828402

Verify or expand the search:

Other recruiting trials for Covid19

Currently open trials in the same condition.

NCT03305341 — Proof-of-Concept Clinical Pharmacology Trial for COVID-19 Antigen Presentation Therapeutic Biologic Mix · EARLY_PHASE1 · active not recruiting
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NCT04924803 — Community Developed Technology-Based Messaging to Increase COVID-19 Vaccine Uptake Among People Who Inject Drugs · NA · active not recruiting
NCT05013632 — COVID-19 International Drug Pregnancy Registry · recruiting
NCT04806061 — Urine Alkalinisation in COVID-19 · NA · active not recruiting

Other Centre Hospitalier Régional Metz-Thionville trials

Trials by the same sponsor.

NCT07435389 — VENTILATION DURING SPACEFLIGHT (PHASE 2) · NA · not yet recruiting
NCT07405996 — Referral of Patients With Biological Abnormalities to an Emergency Department · not yet recruiting
NCT07406022 — Optical Characterization and Multi-modality, Multi-scale Modeling of Human Skin Applied to Cancer Diagnosis. · not yet recruiting
NCT07515404 — A New Multimodal and Semi-specific Therapeutic Plasmapheresis Concept, a Case Series Study · completed
NCT07390604 — Case Series : Management of Elevated Lipoprotein(a) Using Double-Filtration Plasmapheresis (DFPP) in Hemodialysis Patien · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04906850 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Régional Metz-Thionville
Last refreshed: 2 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04906850.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing