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NCT04906330
Oncoliq: Test for Early Breast Cancer Detection.
trial testing Oncoliq: test for early breast cancer detection. in Breast Cancer in 500 participants. Status unknown.
1 August 2024
Quick facts
| Lead sponsor | Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 500 |
| Start date | 1 September 2021 |
| Primary completion | 1 August 2024 |
| Estimated completion | 1 August 2025 |
| Sites | 1 location across Argentina |
Drugs / interventions tested
- Oncoliq: test for early breast cancer detection.
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
Sponsor
Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich
Who can join
Adults 50 to 70, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Oncoliq is a novel early breast cancer detection test based on liquid biopsies and microRNAs. This innovative test will allow improving the accuracy of cancer detection which will impact on health, reducing the patient mortality and health costs. To develop this test, it has been finished the preclinical PHASE I: in laboratory animals; PHASE II: exploratory clinical phase for the discovery of candidate biomarkers in breast cancer patients and PHASE III: clinical validation of biomarkers showing that Oncoliq has 91% of sensitivity. Currently it is been setting up a "pilot test" for breast cancer to enrol 500 woman volunteers without previous cancer diagnosis that go to the annual medical control. The results of the pilot test will give the accuracy for early breast cancer detection.
Publications & conference data
5 peer-reviewed publications reference this trial (live from Europe PMC):
-
Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives.
Seif F, Torki Z, Zalpoor H, Habibi M, et al · · 2023 · cited 31× · PMID 36816749 · DOI 10.1016/j.omto.2023.01.001 -
Addressing the Clinical Feasibility of Adopting Circulating miRNA for Breast Cancer Detection, Monitoring and Management with Artificial Intelligence and Machine Learning Platforms.
Ling L, Aldoghachi AF, Chong ZX, Ho WY, et al · · 2022 · cited 12× · PMID 36499713 · DOI 10.3390/ijms232315382 -
Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.
Beňačka R, Szabóová D, Guľašová Z, Hertelyová Z. · · 2024 · cited 7× · PMID 39795985 · DOI 10.3390/ijms26010127 -
Potential Impact of Preoperative Circulating Biomarkers on Individual Escalating/de-Escalating Strategies in Early Breast Cancer.
Gianni C, Palleschi M, Merloni F, Bleve S, et al · · 2022 · cited 4× · PMID 36612091 · DOI 10.3390/cancers15010096 -
Ambivalent roles of miRNAs in cancer development via modulating tumor-associated innate immune cells.
Naseri B, Mardi A, Shekari N, Shajari N, et al · · 2025 · PMID 41409584 · DOI 10.34172/bi.31430
Verify or expand the search:
- PubMed search for NCT04906330
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04906330 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich
- Last refreshed: 28 February 2024
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