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NCT04905953
Comparison Of Different Doses Of Intrathecal Neostigmine In Prevention Of Post-Dural Puncture Headache
Phase 2, PHASE3 trial testing Neostigmine in Headache in 274 participants. Status unknown.
1 February 2022
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 274 |
| Start date | 1 February 2021 |
| Primary completion | 1 February 2022 |
| Estimated completion | 1 May 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Neostigmine (NEOSTIGMINE) — full drug profile →
Conditions studied
- Headache — all drugs for Headache →
Sponsor
Cairo University
Who can join
Adults 18 to 45, female only, with Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
We hypothesized that; intrathecal administration of neostgmine in spinal anesthesia may have a beneficial role in reduction of the incidence or severity of PDPH.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04905953
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Related trials
Other trials of Neostigmine
Trials testing the same drug.
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- NCT06729047 — Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Pati · Phase 1, PHASE2 · not yet recruiting
- NCT06982092 — Using Diaphragm Ultrasonography, Sugammadex Recovers Diaphragmatic Function More Effectively Than Neostigmine. · Phase 1 · completed
Other recruiting trials for Headache
Currently open trials in the same condition.
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Other Cairo University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04905953 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 28 May 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04905953.
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