Last reviewed · How we verify
NCT04905797
Aspects of Self-harm - Cognition, Imaging and Treatability
trial testing Emotional Stop Signal Task in Self-Harm, Deliberate in 300 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Region Skane |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 30 April 2021 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Emotional Stop Signal Task
- Magnetic Resonance Imaging
- World Health Organizations Disability Assessment Schedule (WHODAS 2.0)
- Personality Inventory for DSM-5 (PID-5)
- Stop Signal Task (CANTAB)
- Intra-Extra Dimensional Set Shift (CANTAB)
- Spatial Working Memory Test (CANTAB)
- Multitasking Test (CANTAB)
- Cambridge Gambling Task Test
Conditions studied
- Self-Harm, Deliberate — all drugs for Self-Harm, Deliberate →
- Non-Suicidal Self Injury — all drugs for Non-Suicidal Self Injury →
- Attempt Suicide — all drugs for Attempt Suicide →
- Personality Disorders — all drugs for Personality Disorders →
Sponsor
Region Skane — full company profile →
Who can join
Adults 18 to 65, any sex, with Self-Harm, Deliberate or Non-Suicidal Self Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Deliberate self-harm (DSH) is a common symptom in psychiatric disorders. This study aim at increased understanding of parameters associated with DSH with the long term goal to potentially improve and possibly personalise its treatment. In short, the study will characterise cognitive, psychiatric and demographic factors with focus on executive function and will compare results from individuals with DSH, individuals who have ceased DSH as well as psychiatric patients without DSH and individuals who never engaged in DSH. Adequate statistical tests will be used to compare groups. Participants will be interviewed by a trained physician for basic medical history, history of self-harm and treatment for that, demographic data and diagnostic evaluation. Thereafter the participants will undergo standardised neuropsychological testing focusing on emotional response inhibition, decision making and risk taking, attention set shifting, working memory, inhibition and planning. Some participants will redo parts of this testing during fMRI, as well as undergo DTI and volumetry.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04905797
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Region Skane trials
Trials by the same sponsor.
- NCT07511673 — The Study is a Randomised Clinical Trial (RCT) to Test if Preoperative Dental Screening is Superior to no Preoperative D · NA · not yet recruiting
- NCT07169747 — Safety, Therapeutic Potential, and Mechanisms of Two Psilocybin Doses, Administered With Psychological Support in Young · Phase 2 · recruiting
- NCT07494669 — Proteomics and Physiological Parameters Predicting Complications After Colorectal Cancer Surgery · not yet recruiting
- NCT07462351 — System-integrated Point-of-Care Ultrasound in Breast Cancer Screening · NA · recruiting
- NCT06975696 — Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04905797 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Region Skane
- Last refreshed: 6 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04905797.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing