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NCT04903782: PREDICT

Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer

Recruiting now Last updated 4 November 2022
What this trial tests

trial testing Family-based whole genome sequencing in Neoplastic Syndromes, Hereditary in 270 participants. Currently enrolling.

Timeline
8 March 2021
Primary endpoint
8 March 2023
15 June 2028

Quick facts

Lead sponsorSydney Children's Hospitals Network
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment270
Start date8 March 2021
Primary completion8 March 2023
Estimated completion15 June 2028
Sites3 locations across Australia

Drugs / interventions tested

Conditions studied

Sponsor

Sydney Children's Hospitals Network

Who can join

Under 21, any sex, with Neoplastic Syndromes, Hereditary or Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Assessment of the utility of family-based (trio) whole-genome sequencing for cancer predisposition testing in sequential newly diagnosed paediatric and adolescent cancer patients

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.
    Fuentes Bolanos NA, Padhye B, Daley M, Hunter J, et al · · 2023 · cited 5× · PMID 37253493 · DOI 10.1136/bmjopen-2022-070082

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Other Sydney Children's Hospitals Network trials

Trials by the same sponsor.

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