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NCT04899011
Taste Disturbance After Middle Ear Surgery: Frequency, Duration, Influence of Chorda Tympani Injury and Quality of Life
trial testing Questionnaire in Ear Middle Problems in 214 participants. Completed in 23 May 2023.
23 May 2023
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Nice |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 214 |
| Start date | 30 May 2021 |
| Primary completion | 23 May 2023 |
| Estimated completion | 23 May 2023 |
| Sites | 1 location across France |
Drugs / interventions tested
- Questionnaire
Conditions studied
- Ear Middle Problems — all drugs for Ear Middle Problems →
Sponsor
Centre Hospitalier Universitaire de Nice
Who can join
Eligibility, any sex, with Ear Middle Problems. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chorda tympani nerve (CTN), is a branch of nerve VII, and has two componants: taste sensation from the anterior two thirds of the tongue and salivary secretion from submandibular and sublingual salivary glands. CTN go throw middle ear between malleus and incus. Due to it anatomic localization, CTN is frequently damage during otologic surgery. Taste disturbance after middle ear surgery has been describe in literature but results of the various studies are very heterogenous. Moreover, there is no consensus to preserved or sacrificed a traumatize CTN. We will use questionnaire to evaluate frequency, duration and characteristics of taste disturbance after ear surgery and the impact on the quality of life for those with symptoms. We will evaluate the Influence of type of CTN injury on taste disturbance.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Taste Disorders After Middle Ear Surgery: Chorda Tympani Nerve Injury and Quality of Life.
Lafargue B, D'Andréa G, Fabre R, Alshukry A, et al · · 2024 · cited 3× · PMID 39087766 · DOI 10.1002/ohn.920
Verify or expand the search:
- PubMed search for NCT04899011
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04899011 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nice
- Last refreshed: 10 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04899011.
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