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Dietary Fructose on Microbiota and Hepatosteatosis
The consumption of sugar-sweetened beverages (SSB) has increased steadily over the past decades, resulting in the dramatic increase of fructose intake as it is one of the main ingredients of artificial sweeteners. Recently, large epidemiological studies have documented the association between a high-fructose-diet and hepatic steatosis, and other metabolic disorders. So it is interesting for scientists to explore the underlying mechanism. This study aims to investigate the effect of dietary fructose and gut microbiota and the hepatosteatosis in healthy men. Serum and fecal metabolomics will be investigated.
Details
| Lead sponsor | Shanghai Zhongshan Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 58 |
| Start date | Tue Jun 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat Dec 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Hepatic Steatosis
- Dietary Fructose Exposure
Interventions
- 75g fructose solution
- 150g fructose solution
Countries
China