NCT04897256 is a NA clinical trial of TURN-IT exercise program in Parkinson Disease, sponsored by Oregon Health and Science University.

Who is sponsoring NCT04897256?

NCT04897256 is sponsored by Oregon Health and Science University.

What drugs are being tested in NCT04897256?

Interventions in NCT04897256: TURN-IT exercise program.

What condition does NCT04897256 study?

NCT04897256 studies Parkinson Disease.

Is NCT04897256 still recruiting?

NCT04897256 is currently active, enrolled. Last updated 17 November 2025.

Last reviewed 2025-11-17 · How we verify

NCT04897256

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Mobility in Daily Life and Falls in Parkinson's Disease: Potential for Rehabilitation

Active, enrolled NA Last updated 17 November 2025

What this trial tests

NA trial testing TURN-IT exercise program in Parkinson Disease in 55 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

13 September 2021

Primary endpoint
30 June 2025

1 June 2026

Quick facts

Lead sponsor	Oregon Health and Science University
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	55
Start date	13 September 2021
Primary completion	30 June 2025
Estimated completion	1 June 2026
Sites	1 location across United States

Drugs / interventions tested

TURN-IT exercise program

Conditions studied

Parkinson Disease — all drugs for Parkinson Disease →

Sponsor

Oregon Health and Science University

Who can join

Adults 55 to 85, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this intervention is to explore the effectiveness of a Turning Intervention (TURN-IT) to improve quality of turning in participants with Parkinson's Disease (PD). An unique exercise program has been developed - TURN-IT - in which participants practice exercises that focus on physiological constraints that impair turning ability, such as axial rigidity, narrow base of support, bradykinesia, and inflexible set-shifting. The 60 participants with PD and a history of falls in the previous 12 months, will be randomized into a 6-week, 3x/week, one-on-one TURN-IT group or No-Intervention Control group. This pilot intervention study will determine the number of subjects needed for a future clinical trial and will determine the sensitivity to change with rehabilitation our daily-life turning quality measures (such as, mean and variability of number of steps to turn, turn amplitude, turn velocity). The investigators predict that the TURN-IT program will improve turning in daily life enough to justify a larger clinical trial.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Interventions for preventing falls in Parkinson's disease.
Allen NE, Canning CG, Almeida LRS, Bloem BR, et al · · 2022 · cited 50× · PMID 35665915 · DOI 10.1002/14651858.cd011574.pub2
TURN-IT: a novel turning intervention program to improve quality of turning in daily life in people with Parkinson's disease.
King LA, Carlson-Kuhta P, Wilhelm JL, Lapidus JA, et al · · 2022 · cited 5× · PMID 36443737 · DOI 10.1186/s12883-022-02934-5

Verify or expand the search:

Other recruiting trials for Parkinson Disease

Currently open trials in the same condition.

NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting

Other Oregon Health and Science University trials

Trials by the same sponsor.

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NCT07309757 — Maternal Outcomes With Methamphetamine Use and Cardiac Assessment for Rural Dissemination (MOM CARD) · not yet recruiting
NCT07282639 — App-Based Certified Diabetes Education Therapy (AB-CDE) · NA · not yet recruiting
NCT07322588 — Reentry Incentives and Support for Engagement With Contingency Management · NA · not yet recruiting
NCT07220590 — Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04897256 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Oregon Health and Science University
Last refreshed: 17 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04897256.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing